Anti-Cancer Properties of Resveratrol: A Focus on Its Impact on Mitochondrial Functions

L Kursvietiene, DM Kopustinskiene, I Staneviciene… - Antioxidants, 2023 - mdpi.com
Cancer is one of the most serious public health issues worldwide, demanding ongoing
efforts to find novel therapeutic agents and approaches. Amid growing interest in the …

Initiation of cancer: The journey from mutations in somatic cells to epigenetic changes in tissue-resident VSELs

D Bhartiya, S Raouf, K Pansare, A Tripathi… - Stem Cell Reviews and …, 2024 - Springer
Multiple theories exist to explain cancer initiation, although a consensus on this is crucial for
developing effective therapies.'Somatic mutation theory'suggests that mutations in somatic …

Preclinical evidence for preventive and curative effects of resveratrol on xenograft cholangiocarcinogenesis

S Thongchot, A Ferraresi, C Vidoni, A Salwa, L Vallino… - Cancer Letters, 2024 - Elsevier
Cholangiocarcinoma (CCA), the malignant tumor of bile duct epithelial cells, is a relatively
rare yet highly lethal cancer. In this work, we tested the ability of Resveratrol (RV) to prevent …

Enhancing the Bioavailability of Resveratrol: Combine It, Derivatize It, or Encapsulate It?

M Salla, N Karaki, B El Kaderi, AJ Ayoub, S Younes… - Pharmaceutics, 2024 - mdpi.com
Overcoming the limited bioavailability and extensive metabolism of effective in vitro drugs
remains a challenge that limits the translation of promising drugs into clinical trials …

Unveiling the multifaceted antiproliferative efficacy of Cichorium endivia root extract by dual modulation of apoptotic and inflammatory genes, inducing cell cycle arrest …

AR Alzahrani, N Hosny, DI Mohamed, HHA Nahas… - RSC …, 2024 - pubs.rsc.org
Chicory (Cichorium endivia L. divaricatum) is a renowned medicinal plant traditionally used
for various ailments, yet the pharmacological potential of its roots, particularly in terms of …

Hyponatremia Promotes Cancer Growth in a Murine Xenograft Model of Neuroblastoma

G Marroncini, L Naldi, B Fibbi, A Errico… - International Journal of …, 2023 - mdpi.com
In cancer patients, hyponatremia is detected in about 40% of cases at hospital admission
and has been associated to a worse outcome. We have previously observed that cancer …

Optimized Ultrasound-Assisted Extraction of Psidium laruotteanum Roots: A Concentrated Source of Piceid from the Brazilian Savanna

LK Takao, W Setyaningsih, SCJ Gualtieri… - Forests, 2023 - mdpi.com
Psidium laruotteanum is a subshrub Myrtaceae, native to the Brazilian savanna, and
distributed in Central and South America. Here, the health beneficial compound piceid …