[HTML][HTML] Mitochondrial dysfunction, oxidative stress, and therapeutic strategies in diabetes, obesity, and cardiovascular disease

KA Cojocaru, I Luchian, A Goriuc, LM Antoci… - Antioxidants, 2023 - mdpi.com
Mitochondria are subcellular organelles involved in essential cellular functions, including
cytosolic calcium regulation, cell apoptosis, and reactive oxygen species production. They …

[HTML][HTML] Targeting oxidative stress as a preventive and therapeutic approach for cardiovascular disease

Q Yan, S Liu, Y Sun, C Chen, S Yang, M Lin… - Journal of Translational …, 2023 - Springer
Cardiovascular diseases (CVDs) continue to exert a significant impact on global mortality
rates, encompassing conditions like pulmonary arterial hypertension (PAH), atherosclerosis …

[HTML][HTML] Therapeutic potential of polyphenols and other micronutrients of marine origin

L Pereira, J Cotas - Marine drugs, 2023 - mdpi.com
Polyphenols are compounds found in various plants and foods, known for their antioxidant
and anti-inflammatory properties. Recently, researchers have been exploring the therapeutic …

[HTML][HTML] Therapeutic potential and limitations of curcumin as antimetastatic agent

P Dytrych, Z Kejík, J Hajduch, R Kaplánek… - Biomedicine & …, 2023 - Elsevier
Abstract Treatment of metastatic cancer is one of the biggest challenges in anticancer
therapy. Curcumin is interesting nature polyphenolic compound with unique biological and …

[HTML][HTML] Mitochondria as novel mediators linking gut microbiota to atherosclerosis that is ameliorated by herbal medicine: A review

Y Li, S Yang, X Jin, D Li, J Lu, X Wang… - Frontiers in …, 2023 - frontiersin.org
Atherosclerosis (AS) is the main cause of cardiovascular disease (CVD) and is
characterized by endothelial damage, lipid deposition, and chronic inflammation. Gut …

Effects of curcumin on blood pressure: A systematic review and dose-response meta-analysis

A Karimi, AM Jazani, M Darzi, RND Azgomi… - Nutrition, Metabolism and …, 2023 - Elsevier
Aims This systematic review and dose-response meta-analysis were conducted to
summarize data from available clinical trials on the effects of curcumin supplementation on …

[HTML][HTML] Curcumin attenuates periodontal injury via inhibiting Ferroptosis of ligature-induced periodontitis in mice

Y Wang, H Lin, W Huang, Z Liu, Z Chen… - International Journal of …, 2023 - mdpi.com
Periodontitis is a chronic infectious disease characterized by the destruction of connective
tissue and alveolar bone that eventually leads to tooth loss. Ferroptosis is an iron-dependent …

[HTML][HTML] Cardiovascular disease treatment using traditional Chinese medicine: Mitochondria as the Achilles' heel

J Gao, T Hou - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Cardiovascular disease (CVD), involving the pathological alteration of the heart or blood
vessels, is one of the main causes of disability and death worldwide, with an estimated 18.6 …

[HTML][HTML] New Insights into Antioxidant Peptides: An Overview of Efficient Screening, Evaluation Models, Molecular Mechanisms, and Applications

Y Zhang, Y Li, Z Quan, P Xiao, JA Duan - Antioxidants, 2024 - mdpi.com
Antioxidant peptides are currently a hotspot in food science, pharmaceuticals, and
cosmetics. In different fields, the screening, activity evaluation, mechanisms, and …

Alternations in interleukin-1β and nuclear factor kappa beta activity (NF-kB) in rat liver due to the co-exposure of Cadmium and Arsenic: Protective role of curcumin

M Cengiz, B Gür, CV Sezer, BP Cengiz, F Gür… - Environmental …, 2023 - Elsevier
Cadmium chloride (Cd) and sodium arsenite (As) are two prominent examples of non-
biodegradable substances that accumulate in ecosystems, pose a serious risk to human …