The past 20 years have witnessed enormous progress in synthetic biology in the
development of engineered cells for diverse applications, including biomanufacturing …

Acinetobacter baylyi ADP1 is a non-pathogenic soil bacterium known for its metabolic
diversity and high natural transformation and recombination efficiency. For these features, A …

Microbial terephthalic acid (TPA) catabolic pathways are conserved among the few bacteria
known to turnover this xenobiotic aromatic compound. However, to date there are few …

工业微生物底盘细胞的开发将为工业生物技术的发展提供优良的细胞工厂,
有利于实现环境保护及经济可持续发展. 基于合成生物学“设计-构建-测试-学习”(Design-Build …

One primary objective of synthetic biology is to improve the sustainability of chemical
manufacturing. Naturally occurring biological systems can utilize a variety of carbon sources …

Antimicrobial resistance (AMR) is a global health problem with the environment being an
important compartment for the evolution and transmission of AMR. Previous studies showed …

Unwanted evolution of designed DNA sequences limits metabolic and genome engineering
efforts. Engineered functions that are burdensome to host cells and slow their replication are …

Background Because of its tractability and straightforward cultivation, the magnetic
bacterium Magnetospirillum gryphiswaldense has emerged as a model for the analysis of …

Mobile genetic elements drive evolution by disrupting genes and rearranging genomes.
Eukaryotes have evolved epigenetic mechanisms, including DNA methylation and RNA …

Background Lignocellulosic biomass as feedstock has a huge potential for biochemical
production. Still, efficient utilization of hydrolysates derived from lignocellulose is challenged …