Background Advances in ultrasensitive detection of phosphorylated tau (p-tau) in plasma
has enabled the use of blood tests to measure Alzheimer's disease (AD) biomarker …

Background and Objectives Our objective was to determine whether polysomnographic
(PSG) sleep parameters are associated with neuroimaging biomarkers of cerebrovascular …

Abstract Alzheimer's disease (AD), characterized by the deposition of amyloid-β (Aβ) in
senile plaques and neurofibrillary tangles of phosphorylated tau (pTau), is increasingly …

Objectives Active RA has been associated with an increased risk of both cardiovascular and
peripheral vascular disease. We aimed to compare cerebrovascular changes in patients …

Understanding microscale physiology and microstructural cellular features of the brain is key
to understanding mechanisms of neurodegenerative diseases and injury, as well as …

Background: Dementia, vascular disease, and cancer increase with age, enabling complex
comorbid interactions. Understanding vascular and cancer contributions to dementia risk …

This issue of Acta Neuropathologica includes a cluster of four manuscripts that bear the
imprint of John Q. Trojanowski, MD, Ph. D. Having passed away just under 1 year ago, much …

Objective To investigate the association between standard pure tone and speech
audiometry with neuroimaging characteristics reflective of aging and dementia in older …

Background and Objectives Alzheimer disease (AD) is neuropathologically classified into 3
corticolimbic subtypes based on the neurofibrillary tangle distribution throughout the …

This brief statement describes some recent achievements of neuropathological research,
with the focus on Alzheimer's and other age-related diseases, neurodegenerative disorders …