[HTML][HTML] Progression in translational research on spinal cord injury based on microenvironment imbalance

B Fan, Z Wei, S Feng - Bone research, 2022 - nature.com
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …

Advances in triboelectric nanogenerators for self‐powered regenerative medicine

S Parandeh, N Etemadi, M Kharaziha… - Advanced Functional …, 2021 - Wiley Online Library
Over the last decade, in pursuit to provide suitable alternatives for power supplies of medical
devices in regenerative medicine, extensive research on nanogenerators has been …

[HTML][HTML] Effects of transcranial direct current stimulation combined with physical training on the excitability of the motor cortex, physical performance, and motor …

B Wang, S Xiao, C Yu, J Zhou, W Fu - Frontiers in neuroscience, 2021 - frontiersin.org
Purpose: This systematic review aims to examine the efficacy of transcranial direct current
stimulation (tDCS) combined with physical training on the excitability of the motor cortex …

Recent progress and challenges in the treatment of spinal cord injury

T Tian, S Zhang, M Yang - Protein & cell, 2023 - academic.oup.com
Spinal cord injury (SCI) disrupts the structural and functional connectivity between the higher
center and the spinal cord, resulting in severe motor, sensory, and autonomic dysfunction …

Neuroplasticity of spinal cord injury and repair

JH Martin - Handbook of Clinical Neurology, 2022 - Elsevier
The sudden loss of movement after spinal cord injury (SCI) is life-changing and is a major
impetus to study spinal cord motor system plasticity and devise novel repair strategies. This …

Electrical stimulation as a tool to promote plasticity of the injured spinal cord

AS Jack, C Hurd, J Martin, K Fouad - Journal of Neurotrauma, 2020 - liebertpub.com
Unlike their peripheral nervous system counterparts, the capacity of central nervous system
neurons and axons for regeneration after injury is minimal. Although a myriad of therapies …

[HTML][HTML] Chronic neuronal activation increases dynamic microtubules to enhance functional axon regeneration after dorsal root crush injury

DI Wu, Y Jin, TM Shapiro, A Hinduja, PW Baas… - Nature …, 2020 - nature.com
After a dorsal root crush injury, centrally-projecting sensory axons fail to regenerate across
the dorsal root entry zone (DREZ) to extend into the spinal cord. We find that chemogenetic …

[HTML][HTML] Brain delivering RNA-based therapeutic strategies by targeting mTOR pathway for axon regeneration after central nervous system injury

MX Li, JW Weng, ES Ho, SF Chow… - Neural regeneration …, 2022 - journals.lww.com
Injuries to the central nervous system (CNS) such as stroke, brain, and spinal cord trauma
often result in permanent disabilities because adult CNS neurons only exhibit limited axon …

[HTML][HTML] Functional electrical stimulation and the modulation of the axon regeneration program

JS Jara, S Agger, ER Hollis - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
Neural injury in mammals often leads to persistent functional deficits as spontaneous repair
in the peripheral nervous system (PNS) is often incomplete, while endogenous repair …

[HTML][HTML] Composite fibrin/carbon microfiber implants for bridging spinal cord injury: a translational approach in pigs

A Alves-Sampaio, P Del-Cerro… - International Journal of …, 2023 - mdpi.com
Biomaterials may enhance neural repair after spinal cord injury (SCI) and testing their
functionality in large animals is essential to achieve successful clinical translation. This work …