Association between SLCO1B1 genetic polymorphisms and bleeding risk in patients treated with edoxaban
JM Han, EJ Jang, J Yee, TJ Song, DH Kim, J Park… - Scientific Reports, 2023 - nature.com
Since SLCO1B1 encodes the uptake transporter OATP1B1, which can influence the
pharmacokinetic and pharmacodynamic profiles of edoxaban, polymorphisms in SLCO1B1 …
pharmacokinetic and pharmacodynamic profiles of edoxaban, polymorphisms in SLCO1B1 …
Identification of genetic biomarkers associated with pharmacokinetics and pharmacodynamics of apixaban in Chinese healthy volunteers
G Mu, Q Xie, Z Liu, H Zhang, X Meng… - Expert Opinion on …, 2023 - Taylor & Francis
Background Apixaban is a superior direct oral anticoagulant exihibiting interindividual
variability in concentration and response in the real world. The present study aimed to …
variability in concentration and response in the real world. The present study aimed to …
Effect of pregnane X receptor and cytochrome P450 oxidoreductase gene polymorphisms on trough concentrations of rivaroxaban and edoxaban in patients with …
J Nakagawa, T Kinjo, N Aiuchi, K Ueno… - European Journal of …, 2023 - Springer
We recently reported that the genotype status of P450 oxidoreductase (POR)* 28 and the
haplotype status of pregnane X receptor (PXR)* 1B affect the daily dose adjusted-trough …
haplotype status of pregnane X receptor (PXR)* 1B affect the daily dose adjusted-trough …