Redox dysfunctions and neuro-oxidative stress play a major role in the pathophysiology and
progression of Parkinson's disease (PD). Glutathione (GSH) and the reduced/oxidized …

Abstract Significance: The thioredoxin (Trx) and glutathione (GSH) systems play important
roles in maintaining the redox balance in the brain, a tissue that is prone to oxidative stress …

Brain tissue has a remarkable ability to accumulate glutamate. This ability is due to
glutamate transporter proteins present in the plasma membranes of both glial cells and …

The tripeptide glutathione is the thiol compound present in the highest concentration in cells
of all organs. Glutathione has many physiological functions including its involvement in the …

Proton NMR chemical shift and J‐coupling values are presented for 35 metabolites that can
be detected by in vivo or in vitro NMR studies of mammalian brain. Measurements were …

The advance in the area of synthesis and reactivity of organoselenium, as well as the
discovery that selenium was the cause of severe intoxication episodes of livestock in the …

Neurological disorders are common, costly, and can cause enduring disability. Although
mostly unknown, a few environmental toxicants are recognized causes of neurological …

Mercury (Hg) toxicity continues to represent a global health concern. Given that human
populations are mostly exposed to low chronic levels of mercurial compounds …

Quantum dots (QDs) are luminescent nanoparticles with unique optical properties that have
been exploited for single-cell and whole-animal imaging. When coated with proteins or …

The antioxidant glutathione (GSH) is essential for the cellular detoxification of reactive
oxygen species in brain cells. A compromised GSH system in the brain has been connected …