Cystic fibrosis (CF) is caused by defects in an anion channel, the cystic fibrosis
transmembrane conductance regulator (CFTR). Recently, a new airway epithelial cell type …

Introduction One of the most intriguing aspects of male reproductive physiology is the ability
of the epididymis to prevent the mounting of immune responses against the onslaught of …

Spermatozoa acquire their fertilizing ability and forward motility during epididymal transit,
suggesting the importance of the epididymis. Although the cell atlas of the epididymis was …

The evolutionary relationship of cells within tissues having a similar function but located in
different anatomical sites is of considerable biological interest. The development of single …

The widespread application of zinc oxide nanoparticles (ZnO NPs) in our daily life has
initiated an enhanced awareness of their biosafety concern. An incredible boom of evidence …

CFTR (cystic fibrosis transmembrane conductance regulator) is a tightly regulated anion
channel that mediates chloride and bicarbonate conductance in many epithelia and in other …

Single-cell RNA sequencing has recently led to the identification of a flurry of rare, new cell
types, such as the CFTR-high ionocytes in the airway epithelium. Ionocytes appear to be …

During human fetal development, sex differentiation occurs not only in the gonads but also
in the adjacent developing reproductive tract. However, while the cellular composition of …

Cystic fibrosis (CF) is a fatal autosomal recessive disorder caused by the loss of function
mutations within a single gene for the Cystic Fibrosis Transmembrane Conductance …

The mononuclear phagocytic system (MPS) is the primary innate immune cell group in male
reproductive tissues, maintaining the balance of pro-inflammatory and immune tolerance …