[HTML][HTML] Nanoparticles in drug delivery: From history to therapeutic applications

O Afzal, ASA Altamimi, MS Nadeem, SI Alzarea… - Nanomaterials, 2022 - mdpi.com
Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …

[HTML][HTML] Polyacrylic acid nanoplatforms: Antimicrobial, tissue engineering, and cancer theranostic applications

H Arkaban, M Barani, MR Akbarizadeh… - Polymers, 2022 - mdpi.com
Polyacrylic acid (PAA) is a non-toxic, biocompatible, and biodegradable polymer that gained
lots of interest in recent years. PAA nano-derivatives can be obtained by chemical …

Engineered extracellular vesicles as intelligent nanosystems for next-generation nanomedicine

Z Fan, C Jiang, Y Wang, K Wang, J Marsh… - Nanoscale …, 2022 - pubs.rsc.org
Extracellular vesicles (EVs), as natural carriers of bioactive cargo, have a unique
micro/nanostructure, bioactive composition, and characteristic morphology, as well as …

[HTML][HTML] Charge-reversal nanomedicines as a smart bullet for deep tumor penetration

Z Li, Y Gao, W Li, Y Li, H Lv, D Zhang, J Peng… - Smart Materials in …, 2022 - Elsevier
Complex composition and abnormal growth state of cells and tissues in the solid tumor
microenvironment often lead to high density and stiffness different from normal tissues, thus …

[HTML][HTML] Lung cancer therapy using doxorubicin and curcumin combination: Targeted prodrug based, pH sensitive nanomedicine

Y Hong, S Che, B Hui, Y Yang, X Wang, X Zhang… - Biomedicine & …, 2019 - Elsevier
Lung cancer is the leading cause of cancer death worldwide. To overcome the toxic side
effects and multidrug resistance (MDR) during doxorubicin (DOX) chemotherapy, a …

GE11-modified carboxymethyl chitosan micelles to deliver DOXĚPD-L1 siRNA complex for combination of ICD and immune escape inhibition against tumor

P Song, B Wang, Q Pan, T Jiang, X Chen, M Zhang… - Carbohydrate …, 2023 - Elsevier
Programmed cell death-ligand 1 (PD-L1) small interfering RNA (siRNA) achieves tumor
immunotherapy by restoring the immune response of T cells, but the efficacy of PD-1/PD-L1 …

Synergistic combination therapy of lung cancer using paclitaxel-and triptolide-coloaded lipid–polymer hybrid nanoparticles

J Liu, H Cheng, L Han, Z Qiang, X Zhang… - Drug design …, 2018 - Taylor & Francis
Purpose Non-small cell lung cancer (NSCLC) accounts for the majority of lung cancer. Lipid–
polymer hybrid nanoparticles (LPNs) combine the advantages of both polymeric …

Progresses in polymeric nanoparticles for delivery of tyrosine kinase inhibitors

B Foroughi-Nia, J Barar, MY Memar, A Aghanejad… - Life sciences, 2021 - Elsevier
Tyrosine kinase inhibitors (TKIs), as an important class of chemotherapeutic drugs, induce
apoptosis by altering the path of the cellular signal, resulting in cell death. However, some …

[HTML][HTML] Synergistic combination therapy of lung cancer: Cetuximab functionalized nanostructured lipid carriers for the co-delivery of paclitaxel and 5 …

S Guo, Y Zhang, Z Wu, L Zhang, D He, X Li… - Biomedicine & …, 2019 - Elsevier
Lung cancer remains the leading cause of cancer associated deaths worldwide. Recent
efforts have been focused on combinational and nanoparticulate therapies that can …

[HTML][HTML] Non-small cell lung cancer combination therapy: Hyaluronic acid modified, epidermal growth factor receptor targeted, pH sensitive lipid-polymer hybrid …

J Pang, H Xing, Y Sun, S Feng, S Wang - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality in
China. This study aimed to develop a hyaluronic acid (HA) decorated, pH sensitive lipid …