How changes in dopamine D2 receptor levels alter striatal circuit function and motivation
It was first posited, more than five decades ago, that the etiology of schizophrenia involves
overstimulation of dopamine receptors. Since then, advanced clinical research methods …
overstimulation of dopamine receptors. Since then, advanced clinical research methods …
[HTML][HTML] GPCR-based dopamine sensors—a detailed guide to inform sensor choice for in vivo imaging
MA Labouesse, RB Cola, T Patriarchi - International journal of molecular …, 2020 - mdpi.com
Understanding how dopamine (DA) encodes behavior depends on technologies that can
reliably monitor DA release in freely-behaving animals. Recently, red and green genetically …
reliably monitor DA release in freely-behaving animals. Recently, red and green genetically …
Maternal low-dose aspartame and stevia consumption with an obesogenic diet alters metabolism, gut microbiota and mesolimbic reward system in rat dams and their …
JE Nettleton, NA Cho, T Klancic, AC Nicolucci… - Gut, 2020 - gut.bmj.com
Objective We examined the impact of maternal low-dose aspartame and stevia consumption
on adiposity, glucose tolerance, gut microbiota and mesolimbic pathway in obese dams and …
on adiposity, glucose tolerance, gut microbiota and mesolimbic pathway in obese dams and …
A high-fat high-sugar diet in adolescent rats impairs social memory and alters chemical markers characteristic of atypical neuroplasticity and parvalbumin interneuron …
AC Reichelt, GD Gibson, KN Abbott, DJ Hare - Food & function, 2019 - pubs.rsc.org
Brain plasticity is a multifaceted process that is dependent on both neurons and extracellular
matrix (ECM) structures, including perineuronal nets (PNNs). In the medial prefrontal cortex …
matrix (ECM) structures, including perineuronal nets (PNNs). In the medial prefrontal cortex …
[HTML][HTML] Deep brain stimulation for obesity: a review and future directions
The global prevalence of obesity has been steadily increasing. Although pharmacotherapy
and bariatric surgeries can be useful adjuvants in the treatment of morbid obesity, they may …
and bariatric surgeries can be useful adjuvants in the treatment of morbid obesity, they may …
Hypothalamic dopamine signalling regulates brown fat thermogenesis
C Folgueira, D Beiroa, B Porteiro, M Duquenne… - Nature …, 2019 - nature.com
Dopamine signalling is a crucial part of the brain reward system and can affect feeding
behaviour. Dopamine receptors are also expressed in the hypothalamus, which is known to …
behaviour. Dopamine receptors are also expressed in the hypothalamus, which is known to …
[HTML][HTML] Modified in situ Hybridization Chain Reaction Using Short Hairpin DNAs
Y Tsuneoka, H Funato - Frontiers in Molecular Neuroscience, 2020 - frontiersin.org
The visualization of multiple gene expressions in well-preserved tissues is crucial for the
elucidation of physiological and pathological processes. In situ hybridization chain reaction …
elucidation of physiological and pathological processes. In situ hybridization chain reaction …
[HTML][HTML] Fluorescence quenching by high-power LEDs for highly sensitive fluorescence in situ hybridization
Y Tsuneoka, Y Atsumi, A Makanae… - Frontiers in molecular …, 2022 - frontiersin.org
Recent technical advances have made fluorescent in situ hybridization (ISH) a pivotal
method to analyze neural tissue. In a highly sensitive ISH, it is important to reduce tissue …
method to analyze neural tissue. In a highly sensitive ISH, it is important to reduce tissue …
Role of the striatal dopamine, GABA and opioid systems in mediating feeding and fat intake
Food intake, which is a highly reinforcing behavior, provides nutrients required for survival in
all animals. However, when fat and sugar consumption goes beyond the daily needs, it can …
all animals. However, when fat and sugar consumption goes beyond the daily needs, it can …
Dietary lipids as regulators of reward processes: multimodal integration matters
The abundance of energy-dense and palatable diets in the modern food environment tightly
contributes to the obesity pandemic. The reward circuit participates to the regulation of body …
contributes to the obesity pandemic. The reward circuit participates to the regulation of body …