Xylitol: bioproduction and applications-a review

D Umai, R Kayalvizhi, V Kumar, S Jacob - Frontiers in Sustainability, 2022 - frontiersin.org
Xylitol, a natural compound classified as a sugar alcohol, is found diversely in fruits and
vegetables in small quantities. Commercial production of xylitol has expanded due to its …

[HTML][HTML] Scaling up xylitol bioproduction: Challenges to achieve a profitable bioprocess

SS Queiroz, FM Jofre, SI Mussatto… - … and Sustainable Energy …, 2022 - Elsevier
Xylitol is a GRAS (Generally Recognized as Safe) polyol commonly used in the food industry
and able to promote several benefits to the health. In addition, it can also be used as a …

Combination of multi-enzyme expression fine-tuning and co-substrates addition improves phenyllactic acid production with an Escherichia coli whole-cell biocatalyst

Y Hou, B Gao, J Cui, Z Tan, C Qiao, S Jia - Bioresource technology, 2019 - Elsevier
The aim of this study was to develop an environmentally safe and efficient method for
phenyllactic acid (PLA) production using whole-cell cascade catalysis with l-amino acid …

The effect of xylose reductase genes on xylitol production by industrial Saccharomyces cerevisiae in fermentation of glucose and xylose

BX Yang, CY Xie, ZY Xia, YJ Wu, B Li, YQ Tang - Process Biochemistry, 2020 - Elsevier
The co-production of xylitol and ethanol from agricultural straw has more economic
advantages than the production of ethanol only. Saccharomyces cerevisiae, the most widely …

Efficient Biosynthesis of Xylitol from Xylose by Coexpression of Xylose Reductase and Glucose Dehydrogenase in Escherichia coli

LQ Jin, W Xu, B Yang, ZQ Liu, YG Zheng - Applied biochemistry and …, 2019 - Springer
Xylitol is an important functional sugar alcohol which is widely used in industries. To
efficiently produce xylitol from xylose by xylose reductase in a single step, the coupled …

Recent insights, applications and prospects of xylose reductase: a futuristic enzyme for xylitol production

Y Lugani, M Puri, BS Sooch - European Food Research and Technology, 2021 - Springer
Xylose reductase (XR) is an intermediate inducible enzyme of xylose metabolism
responsible for the reduction of xylose into xylitol. It is an intracellular enzyme present in …

Exploiting the NADPH pool for xylitol production using recombinant Saccharomyces cerevisiae

SMS Reshamwala, AM Lali - Biotechnology Progress, 2020 - Wiley Online Library
Xylitol is a five‐carbon sugar alcohol that has a variety of uses in the food and
pharmaceutical industries. In xylose assimilating yeasts, NAD (P) H‐dependent xylose …

A unique xylose reductase from Thermomyces lanuginosus: effect of lignocellulosic substrates and inhibitors and applicability in lignocellulosic bioconversion

M Zhang, AK Puri, Z Wang, S Singh, K Permaul - Bioresource technology, 2019 - Elsevier
In this study, the xylose reductase gene (XRTL) from Thermomyces lanuginosus SSBP was
expressed in Pichia pastoris GS115 and Saccharomyces cerevisiae Y294. The purified 39.2 …

Production of xylitol by Saccharomyces cerevisiae using waste xylose mother liquor and corncob residues

Y He, H Li, L Chen, L Zheng, C Ye, J Hou… - Microbial …, 2021 - Wiley Online Library
Exorbitant outputs of waste xylose mother liquor (WXML) and corncob residue from
commercial‐scale production of xylitol create environmental problems. To reduce the …

Improving xylitol yield by deletion of endogenous xylitol-assimilating genes: a study of industrial Saccharomyces cerevisiae in fermentation of glucose and xylose

BX Yang, CY Xie, ZY Xia, YJ Wu, M Gou… - FEMS Yeast …, 2020 - academic.oup.com
Engineered Saccharomyces cerevisiae can reduce xylose to xylitol. However, in S.
cerevisiae, there are several endogenous enzymes including xylitol dehydrogenase …