[HTML][HTML] Combined oral contraceptives and venous thromboembolism: review and perspective to mitigate the risk

L Morimont, H Haguet, JM Dogné, U Gaspard… - Frontiers in …, 2021 - frontiersin.org
Many factors must be considered and discussed with women when initiating a contraceptive
method and the risk of venous thromboembolism (VTE) is one of them. In this review, we …

Ethinyl estradiol and 17β-estradiol in combined oral contraceptives: pharmacokinetics, pharmacodynamics and risk assessment

FZ Stanczyk, DF Archer, BR Bhavnani - Contraception, 2013 - Elsevier
The need to seek improved combined oral contraceptive (COC) efficacy, with fewer health
risks and better acceptability, has been ongoing since the introduction of COCs more than …

Evaluation of the effect of a new oral contraceptive containing estetrol and drospirenone on hemostasis parameters

J Douxfils, C Klipping, I Duijkers, V Kinet, M Mawet… - Contraception, 2020 - Elsevier
Objective To assess the effect on hemostasis parameters of a new combined oral
contraceptive (COC). Study design In this randomized, single centre, open-label, exploratory …

Prospective controlled cohort study on the safety of a monophasic oral contraceptive containing nomegestrol acetate (2.5 mg) and 17β-oestradiol (1.5 mg)(PRO-E2 …

S Reed, C Koro, J DiBello, K Becker… - … European Journal of …, 2021 - Taylor & Francis
Objective To assess and compare the risk of venous thromboembolism (VTE) and arterial
thromboembolism (ATE) in NOMAC-E2 users with levonorgestrel-containing combined oral …

Systemic hormonal contraception and risk of venous thromboembolism

O Heikinheimo, E Toffol, T Partonen… - Acta obstetricia et …, 2022 - Wiley Online Library
Introduction The increased risk of venous thromboembolism associated with the use of
hormonal contraception is well recognized, but evidence regarding hormonal contraception …

Low thrombin generation in users of a contraceptive containing estetrol and drospirenone

L Morimont, M Jost, U Gaspard… - The Journal of …, 2023 - academic.oup.com
Objective To compare the impact on thrombin generation of the new combined oral
contraceptive containing 15 mg estetrol and 3 mg drospirenone with ethinylestradiol (30 or …

Effects of a monophasic combined oral contraceptive containing nomegestrol acetate and 17β-oestradiol compared with one containing levonorgestrel and …

UM Ågren, M Anttila, K Mäenpää-Liukko… - … European Journal of …, 2011 - Taylor & Francis
Objectives To compare the effects of a combined oral contraceptive (COC) containing
nomegestrol acetate and 17β-oestradiol (NOMAC/E2) on haemostasis, lipids, carbohydrate …

Hormonal and natural contraceptives: a review on efficacy and risks of different methods for an informed choice

AR Genazzani, T Fidecicchi, D Arduini… - Gynecological …, 2023 - Taylor & Francis
The debate about contraception has become increasingly important as more and more
people seek safe and effective contraception. More than 1 billion women of reproductive age …

Hormonal contraceptives and venous thromboembolism: an epidemiological update

G Plu-Bureau, L Maitrot-Mantelet… - Best Practice & …, 2013 - Elsevier
Since the early 1960s, it has been well documented that combined hormonal contraceptives
increase the risk of cardiovascular disease. Newer generation of oral formulations, as well …

Metabolic and haemostatic effects of estradiol valerate/dienogest, a novel oral contraceptive: a randomized, open-label, single-centre study

W Junge, U Mellinger, S Parke, M Serrani - Clinical drug investigation, 2011 - Springer
Abstract Background and Objective: The hormonal components of combined oral
contraceptives (COCs) have various metabolic and haemostatic effects. The objective of this …