Signaling pathways in obesity: mechanisms and therapeutic interventions

X Wen, B Zhang, B Wu, H Xiao, Z Li, R Li… - Signal transduction and …, 2022 - nature.com
Obesity is a complex, chronic disease and global public health challenge. Characterized by
excessive fat accumulation in the body, obesity sharply increases the risk of several …

Pollution and the heart

S Rajagopalan, PJ Landrigan - New England Journal of Medicine, 2021 - Mass Medical Soc
Pollution and the Heart Environmental pollution is a cardiovascular risk factor. The Global
Burden of Disease study estimated that pollution caused 9 million deaths in 2019, of which …

Clinical practice guideline for the evaluation and treatment of children and adolescents with obesity

SE Hampl, SG Hassink, AC Skinner, SC Armstrong… - …, 2023 - publications.aap.org
The current and long-term health of 14.4 million children and adolescents is affected by
obesity, 1, 2 making it one of the most common pediatric chronic diseases. 3–5 Long …

[HTML][HTML] An introduction to the sources, fate, occurrence and effects of endocrine disrupting chemicals released into the environment

CD Metcalfe, S Bayen, M Desrosiers, G Muñoz… - Environmental …, 2022 - Elsevier
Many classes of compounds are known or suspected to disrupt the endocrine system of
vertebrate and invertebrate organisms. This review of the sources and fate of selected …

Groundwater quality and public health

X Xie, J Shi, K Pi, Y Deng, B Yan, L Tong… - Annual Review of …, 2023 - annualreviews.org
Groundwater deterioration due to enrichment with contaminants of either geogenic or
anthropogenic origin has adversely affected safe water supply for drinking and irrigation …

[HTML][HTML] Pesticides in ambient air, influenced by surrounding land use and weather, pose a potential threat to biodiversity and humans

JG Zaller, M Kruse-Plaß, U Schlechtriemen… - Science of the Total …, 2022 - Elsevier
Little is known about (i) how numbers and concentrations of airborne pesticide residues are
influenced by land use, interactions with meteorological parameters, or by substance …

Occurrence, potential ecological risks, and degradation of endocrine disrupter, nonylphenol, from the aqueous environment

G Bhandari, AR Bagheri, P Bhatt, M Bilal - Chemosphere, 2021 - Elsevier
Nonylphenol (NP) is considered a potential endocrine-disrupting chemical affecting humans
and the environment. Due to widespread occurrence in the aquatic environment and neuro …

[HTML][HTML] Non-targeted metabolomics and associations with per-and polyfluoroalkyl substances (PFAS) exposure in humans: A scoping review

P Guo, T Furnary, V Vasiliou, Q Yan, K Nyhan… - Environment …, 2022 - Elsevier
Objective To summarize the application of non-targeted metabolomics in epidemiological
studies that assessed metabolite and metabolic pathway alterations associated with per-and …

The regulation of endocrine-disrupting chemicals to minimize their impact on health

C Duh-Leong, MV Maffini, CD Kassotis… - Nature Reviews …, 2023 - nature.com
Endocrine-disrupting chemicals (EDCs) are substances generated by human industrial
activities that are detrimental to human health through their effects on the endocrine system …

Current insights and emerging trends in early-onset type 2 diabetes

S Misra, C Ke, S Srinivasan, A Goyal… - The Lancet Diabetes & …, 2023 - thelancet.com
Type 2 diabetes diagnosed in childhood or early adulthood is termed early-onset type 2
diabetes. Cases of early-onset type 2 diabetes are increasing rapidly globally, alongside …