A review on the sources, occurrence and health risks of per-/poly-fluoroalkyl substances (PFAS) arising from the manufacture and disposal of electric and electronic …
Electric and electronic waste materials (e-waste) serve as a reservoir of highly persistent
and extremely toxic inorganic and organic hazardous materials, including per-/poly …
and extremely toxic inorganic and organic hazardous materials, including per-/poly …
Perspectives and challenges of epigenetic determinants of childhood obesity: a systematic review
R Alfano, O Robinson, E Handakas, TS Nawrot… - Obesity …, 2022 - Wiley Online Library
The tremendous increase in childhood obesity prevalence over the last few decades cannot
merely be explained by genetics and evolutionary changes in the genome, implying that …
merely be explained by genetics and evolutionary changes in the genome, implying that …
[HTML][HTML] Early-life environmental exposure determinants of child behavior in Europe: a longitudinal, population-based study
Background Environmental exposures in early life influence the development of behavioral
outcomes in children, but research has not considered multiple exposures. We therefore …
outcomes in children, but research has not considered multiple exposures. We therefore …
[HTML][HTML] Multi-omics signatures of the human early life exposome
L Maitre, M Bustamante, C Hernández-Ferrer… - Nature …, 2022 - nature.com
Environmental exposures during early life play a critical role in life-course health, yet the
molecular phenotypes underlying environmental effects on health are poorly understood. In …
molecular phenotypes underlying environmental effects on health are poorly understood. In …
[HTML][HTML] The early-life exposome and epigenetic age acceleration in children
P de Prado-Bert, C Ruiz-Arenas, M Vives-Usano… - Environment …, 2021 - Elsevier
The early-life exposome influences future health and accelerated biological aging has been
proposed as one of the underlying biological mechanisms. We investigated the association …
proposed as one of the underlying biological mechanisms. We investigated the association …
[HTML][HTML] Advancing tools for human early lifecourse exposome research and translation (ATHLETE): Project overview
M Vrijheid, X Basagaña, JR Gonzalez… - Environmental …, 2021 - journals.lww.com
Early life stages are vulnerable to environmental hazards and present important windows of
opportunity for lifelong disease prevention. This makes early life a relevant starting point for …
opportunity for lifelong disease prevention. This makes early life a relevant starting point for …
[HTML][HTML] The exposome approach to decipher the role of multiple environmental and lifestyle determinants in asthma
Asthma is a widespread respiratory disease caused by complex contribution from genetic,
environmental and behavioral factors. For several decades, its sensitivity to environmental …
environmental and behavioral factors. For several decades, its sensitivity to environmental …
[HTML][HTML] Integrating-omics approaches into population-based studies of endocrine disrupting chemicals: A scoping review
Health effects of endocrine disrupting chemicals (EDCs) are challenging to detect in the
general population. Omics technologies become increasingly common to identify early …
general population. Omics technologies become increasingly common to identify early …
Connecting chemical exposome to human health using high‐resolution mass spectrometry‐based biomonitoring: Recent advances and future perspectives
YC Chen, JF Hsu, CW Chang, SW Li… - Mass Spectrometry …, 2023 - Wiley Online Library
Compared with the rapid advances in genomics leading to broad understanding of human
disease, the linkage between chemical exposome and diseases is still under investigation …
disease, the linkage between chemical exposome and diseases is still under investigation …
[HTML][HTML] The exposome approach to study children's health
E Handakas, O Robinson, JE Laine - Current Opinion in Environmental …, 2023 - Elsevier
The exposome represents an interdisciplinary science and promising field of research that
can identify how multiple facets of the environment influences health across the lifespan. A …
can identify how multiple facets of the environment influences health across the lifespan. A …