Glycogen synthase kinase-3 (GSK-3) is a ubiquitously expressed serine/threonine kinase
with a plethora of substrates. As a modulator of several cellular processes, GSK-3 has a …

Amyloid-beta (Aß) and hyperphosphorylated tau are hallmark lesions of Alzheimer's disease
(AD). However, the loss of synapses and dysfunctions of neurotransmission are more …

Alzheimer's disease (AD) is the foremost type of dementia that afflicts considerable morbidity
and mortality in aged population. Several transcription molecules, pathways, and molecular …

G protein-coupled dopamine receptors (D1, D2, D3, D4, and D5) mediate all of the
physiological functions of the catecholaminergic neurotransmitter dopamine, ranging from …

Dopamine (DA) is one of the major neurotransmitters and participates in a number of
functions such as motor coordination, emotions, memory, reward mechanism …

The roles of the Wnt signalling pathway in several developmental processes, including
synaptic differentiation, are well characterized. The expression of Wnt ligands and Wnt …

The effects of transcranial direct current stimulation (tDCS) on brain functions and the
underlying molecular mechanisms are yet largely unknown. Here we report that mice …

Inhibiting glycogen synthase kinase-3 (GSK-3) activity via pharmacological intervention has
become an important strategy for treating neurodegenerative and psychiatric disorders. The …

This paper reviews new drug targets in the treatment of depression and new drug
candidates to treat depression. Depression is characterized by aberrations in six intertwined …

Psychotropic drugs acting on monoamine neurotransmission are major pharmacological
treatments for neuropsychiatric conditions such as schizophrenia, depression, bipolar …