The knee joint is a complex mechanical system, and computational modelling can provide
vital information for the prediction of disease progression and of the potential for therapeutic …

Osteoarthritis (OA) is a degenerative disease that affects the synovial joints, especially the
knee joint, diminishing the ability of patients to perform daily physical activities …

We propose a method for automatic segmentation of individual muscles from a clinical CT.
The method uses Bayesian convolutional neural networks with the U-Net architecture, using …

Musculoskeletal models provide non-invasive and subject-specific biomechanical
investigations of the musculoskeletal system. In a musculoskeletal model, muscle forces …

Background and objective The dynamic characteristics of the intact knee joint are valuable
for treating knee osteoarthritis and designing knee prostheses. However, it remains a …

Abstract Representation of realistic muscle geometries is needed for systematic
biomechanical simulation of musculoskeletal systems. Most of the previous musculoskeletal …

The Knee contact force (KCF) is a key factor in evaluating knee joint function of patients with
knee osteoarthritis. In vivo measurement of KCF based on the instrumented implants is …

Simulation studies, such as finite element (FE) modeling, provide insight into knee joint
mechanics without patient involvement. Generic FE models mimic the biomechanical …

Many patients suffering from oral and maxillofacial tumors cannot open their mouths wide
after mandibular reconstruction surgery. Musculoskeletal multibody modeling could be a …

A novel reconstructive prosthesis was designed with topological optimization (TO) and a
lattice structure to enhance biomechanical and biological properties in the proximal tibia …