Structural centrosome aberrations promote non‐cell‐autonomous invasiveness
Centrosomes are the main microtubule‐organizing centers of animal cells. Although
centrosome aberrations are common in tumors, their consequences remain subject to …
centrosome aberrations are common in tumors, their consequences remain subject to …
Cardiac myoediting attenuates cardiac abnormalities in human and mouse models of Duchenne muscular dystrophy
Rationale: Absence of dystrophin in Duchenne muscular dystrophy (DMD) results in the
degeneration of skeletal and cardiac muscles. Owing to advances in respiratory …
degeneration of skeletal and cardiac muscles. Owing to advances in respiratory …
The emerging roles of nicotinamide adenine dinucleotide phosphate oxidase 2 in skeletal muscle redox signaling and metabolism
C Henriquez-Olguin, S Boronat… - Antioxidants & Redox …, 2019 - liebertpub.com
Significance: Skeletal muscle is a crucial tissue to whole-body locomotion and metabolic
health. Reactive oxygen species (ROS) have emerged as intracellular messengers …
health. Reactive oxygen species (ROS) have emerged as intracellular messengers …
Targeting microtubules for the treatment of heart disease
EF Warner, Y Li, X Li - Circulation Research, 2022 - Am Heart Assoc
Heart disease remains the leading cause of morbidity and mortality worldwide. With the
advancement of modern technology, the role (s) of microtubules in the pathogenesis of heart …
advancement of modern technology, the role (s) of microtubules in the pathogenesis of heart …
[HTML][HTML] Essential roles of the dystrophin-glycoprotein complex in different cardiac pathologies
IC Valera, AL Wacker, HS Hwang, C Holmes… - Advances in medical …, 2021 - Elsevier
The dystrophin-glycoprotein complex (DGC), situated at the sarcolemma dynamically
remodels during cardiac disease. This review examines DGC remodeling as a common …
remodels during cardiac disease. This review examines DGC remodeling as a common …
NADPH oxidase mediates microtubule alterations and diaphragm dysfunction in dystrophic mice
Skeletal muscle from mdx mice is characterized by increased Nox2 ROS, altered
microtubule network, increased muscle stiffness, and decreased muscle/respiratory function …
microtubule network, increased muscle stiffness, and decreased muscle/respiratory function …
Multi-omics analysis of sarcospan overexpression in mdx skeletal muscle reveals compensatory remodeling of cytoskeleton-matrix interactions that promote …
JL McCourt, KM Stearns-Reider, H Mamsa, P Kannan… - Skeletal muscle, 2023 - Springer
Background The dystrophin-glycoprotein complex (DGC) is a critical adhesion complex of
the muscle cell membrane, providing a mechanical link between the extracellular matrix …
the muscle cell membrane, providing a mechanical link between the extracellular matrix …
[HTML][HTML] A systems approach using the functional resonance analysis method to support fluoride varnish application for children attending general dental practice
Abstract Background All children attending General Dental Practice in Scotland are
recommended to receive twice-yearly applications of sodium fluoride varnish to prevent …
recommended to receive twice-yearly applications of sodium fluoride varnish to prevent …
[HTML][HTML] Rabbit models of cardiac mechano-electric and mechano-mechanical coupling
Cardiac auto-regulation involves integrated regulatory loops linking electrics and mechanics
in the heart. Whereas mechanical activity is usually seen as 'the endpoint'of cardiac auto …
in the heart. Whereas mechanical activity is usually seen as 'the endpoint'of cardiac auto …