Precision medicine is being enabled in high-income countries by the growing availability of
health data, increasing knowledge of the genetic determinants of disease and variation in …

Introduction Schizophrenia and bipolar disorder account for a large proportion of the global
burden of disease. Despite their enormous impact, little is known about their …

Africa was previously insufficiently represented in the emerging discipline of biobanking
despite commendable early efforts. However, with the Human, Heredity, and Health in Africa …

Evidence-based healthcare relies on health data from diverse sources to inform decision-
making across different domains, including disease prevention, aetiology, diagnostics …

Low-and middle-income countries (LMIC) constitute the majority of the world's population
and bear more than 80% of the global burden of cardiovascular disease (CVD). 1, 2 The …

The establishment of Human Heredity and Health in Africa (H3Africa. www. h3africa. org)
has catalyzed collaborative research across national boundaries, building on existing …

Background Biorepositories archive and distribute well-characterized biospecimens for
research to support the development of medical diagnostics and therapeutics. Knowledge of …

Recent technological advances have allowed the unprecedented generation of large data
sets in the biological sciences. Gaining the most value from this generation requires the data …

Background: Genetic diversity is abundant on the African continent. However, genomic
research has been hampered by a lack of high quality and extensively annotated …

Biobanks and human genomics applications are key for understanding health, disease and
heredity in Africa and globally. Growing interest in these technologies calls for strengthening …