Microfluidics-based strategies for molecular diagnostics of infectious diseases

X Wang, XZ Hong, YW Li, Y Li, J Wang, P Chen… - Military Medical …, 2022 - Springer
Traditional diagnostic strategies for infectious disease detection require benchtop
instruments that are inappropriate for point-of-care testing (POCT). Emerging microfluidics, a …

Millifluidics, microfluidics, and nanofluidics: manipulating fluids at varying length scales

L Chen, C Yang, Y Xiao, X Yan, L Hu… - Materials Today …, 2021 - Elsevier
Manipulating fluids at varying length scales and understanding their underlying mechanisms
are significant for interdisciplinary studies of physics, chemistry, biology, and engineering; …

Rapid electrochemical detection of coronavirus SARS-CoV-2

T Chaibun, J Puenpa, T Ngamdee… - Nature …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Diagnosis of COVID-19 …

COVID-19 diagnosis: current and future techniques

A Sharma, S Balda, M Apreja, K Kataria… - International Journal of …, 2021 - Elsevier
COVID-19 pandemic continues to be a global threat, affecting more than 200
countries/territories at both human and economic level. This necessitates the rapid …

Graphene oxide-based colorimetric/fluorescence dual-mode immunochromatography assay for simultaneous ultrasensitive detection of respiratory virus and bacteria …

X Cheng, X Yang, Z Tu, Z Rong, C Wang… - Journal of Hazardous …, 2023 - Elsevier
Highlights•The first 2D colorimetric/fluorescence dual-signal tag used for ICA
method.•Sensitivity improved by 10 and 500 times in colorimetric mode and fluorescence …

Nucleic acid testing of SARS-CoV-2

HM Yoo, IH Kim, S Kim - International Journal of Molecular Sciences, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19) has caused a large global outbreak. It is
accordingly important to develop accurate and rapid diagnostic methods. The polymerase …

Toward rapid and accurate molecular diagnostics at home

W Liu, LP Lee - Advanced Materials, 2023 - Wiley Online Library
The global outbreaks of infectious diseases have significantly driven an imperative demand
for rapid and accurate molecular diagnostics. Nucleic acid amplification tests (NAATs) …

Sensitive and Rapid Diagnosis of Respiratory Virus Coinfection Using a Microfluidic Chip‐Powered CRISPR/Cas12a System

J Liu, H Wang, L Zhang, Y Lu, X Wang, M Shen, N Li… - Small, 2022 - Wiley Online Library
The ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 is
profoundly influencing the global healthcare system and people's daily lives. The high …

SARS-CoV-2 diagnostics based on nucleic acids amplification: from fundamental concepts to applications and beyond

JM Vindeirinho, E Pinho, NF Azevedo… - Frontiers in cellular and …, 2022 - frontiersin.org
COVID-19 pandemic ignited the development of countless molecular methods for the
diagnosis of SARS-CoV-2 based either on nucleic acid, or protein analysis, with the first …

Integrated microfluidic devices for point-of-care detection of bio-analytes and disease

PP Behera, N Kumar, M Kumari, S Kumar… - Sensors & …, 2023 - pubs.rsc.org
Micro-and nanofluidics have enabled the possibility of miniaturized analytical systems,
which are commonly known as lab-on-a-chip (LOC) devices. One of the clear benefits of …