Chronic pain: structural and functional changes in brain structures and associated negative affective states

S Yang, MC Chang - International journal of molecular sciences, 2019 - mdpi.com
Chronic pain is a condition in which pain progresses from an acute to chronic state and
persists beyond the healing process. Chronic pain impairs function and decreases patients' …

Can insects feel pain? A review of the neural and behavioural evidence

M Gibbons, A Crump, M Barrett, S Sarlak, J Birch… - Advances in Insect …, 2022 - Elsevier
The entomology literature has historically suggested insects cannot feel pain, leading to
their exclusion from ethical debates and animal welfare legislation. However, there may be …

Neuropeptide Y is an immunomodulatory factor: direct and indirect

W Chen, Y Liu, W Liu, Y Zhou, H He, S Lin - Frontiers in immunology, 2020 - frontiersin.org
Neuropeptide Y (NPY), which is widely distributed in the nervous system, is involved in
regulating a variety of biological processes, including food intake, energy metabolism, and …

Spinal neuropeptide Y1 receptor-expressing neurons form an essential excitatory pathway for mechanical itch

D Acton, X Ren, S Di Costanzo, A Dalet, S Bourane… - Cell reports, 2019 - cell.com
Acute itch can be generated by either chemical or mechanical stimuli, which activate
separate pathways in the periphery and spinal cord. While substantial progress has been …

[HTML][HTML] Efficacy and safety of Ciprofol for procedural sedation and anesthesia in non-operating room settings

J Zhong, J Zhang, Y Fan, M Zhu, X Zhao, Z Zuo… - Journal of Clinical …, 2023 - Elsevier
Study objective Ciprofol, a novel intravenous anesthetic, provides rapid recovery in patients
undergoing colonoscopy. We aimed to examine the efficacy and safety of ciprofol in …

Roles of neuropeptide Y in neurodegenerative and neuroimmune diseases

C Li, X Wu, S Liu, Y Zhao, J Zhu, K Liu - Frontiers in Neuroscience, 2019 - frontiersin.org
Neuropeptide Y (NPY) is a neurotransmitter or neuromodulator that mainly exists in the
nervous system. It plays a neuroprotective role in organisms and widely participates in the …

Immunomodulatory role of neuropeptides in the cornea

S Puri, BM Kenyon, P Hamrah - Biomedicines, 2022 - mdpi.com
The transparency of the cornea along with its dense sensory innervation and resident
leukocyte populations make it an ideal tissue to study interactions between the nervous and …

Spinal neuropeptide Y Y1 receptor-expressing neurons are a pharmacotherapeutic target for the alleviation of neuropathic pain

TS Nelson, GP Sinha, DFS Santos… - Proceedings of the …, 2022 - National Acad Sciences
Peripheral nerve injury sensitizes a complex network of spinal cord dorsal horn (DH)
neurons to produce allodynia and neuropathic pain. The identification of a druggable target …

Neuropeptide Y‐mediated gut microbiota alterations aggravate postmenopausal osteoporosis

Z Chen, M Lv, J Liang, K Yang, F Li, Z Zhou… - Advanced …, 2023 - Wiley Online Library
Postmenopausal osteoporosis (PMO) is often accompanied by neuroendocrine changes in
the hypothalamus, which closely associates with the microbial diversity, community …

Pain biomarkers in fibromyalgia syndrome: current understanding and future directions

M Favretti, C Iannuccelli, M Di Franco - International Journal of Molecular …, 2023 - mdpi.com
Fibromyalgia is a complex and heterogeneous clinical syndrome, mainly characterized by
the presence of widespread pain, possibly associated with a variety of other symptoms …