MicroRNAs: Emerging oncogenic and tumor-suppressive regulators, biomarkers and therapeutic targets in lung cancer

S Tang, S Li, T Liu, Y He, H Hu, Y Zhu, S Tang, H Zhou - Cancer Letters, 2021 - Elsevier
Lung cancer is one of the most common solid tumors worldwide and the leading cause of
cancer-related deaths, causing a devastating impact on human health. The clinical …

Pan-cancer analysis of ARID family members as novel biomarkers for immune checkpoint inhibitor therapy

Y Zhu, C Yan, X Wang, Z Xu, J Lv, X Xu… - Cancer biology & …, 2022 - Taylor & Francis
Although immune checkpoint inhibitors (ICIs) have greatly improved cancer treatment, the
accuracy of predictive biomarkers for ICI outcomes, such as PD-L1, TMB (tumor mutation …

Role of cytokines and chemokines in NSCLC immune navigation and proliferation

S Ramachandran, AK Verma, K Dev… - Oxidative medicine …, 2021 - Wiley Online Library
With over a million deaths every year around the world, lung cancer is found to be the most
recurrent cancer among all types. Nonsmall cell lung carcinoma (NSCLC) amounts to about …

[HTML][HTML] PAQR4 promotes chemoresistance in non-small cell lung cancer through inhibiting Nrf2 protein degradation

P Xu, L Jiang, Y Yang, M Wu, B Liu, Y Shi, Q Shen… - Theranostics, 2020 - ncbi.nlm.nih.gov
Purpose: Lung cancer is the leading cause of cancer related deaths worldwide. We have
previously identified many differentially expressed genes (DEGs) from large scale pan …

[HTML][HTML] Development and validation of TACE refractoriness-related diagnostic and prognostic scores and characterization of tumor microenvironment infiltration in …

Q He, J Yang, Y Jin - Frontiers in immunology, 2022 - frontiersin.org
Background Transcatheter arterial chemoembolization LIHC, Liver hepatocellular
carcinoma;(TACE) is a valid therapeutic method for hepatocellular carcinoma (HCC) …

Micelleplexes as nucleic acid delivery systems for cancer-targeted therapies

M Pereira-Silva, I Jarak, C Alvarez-Lorenzo… - Journal of Controlled …, 2020 - Elsevier
Cancer remains one of the leading causes of death worldwide despite significant
therapeutic advancements and improved detection methods. Nucleic acid (NA) therapeutics …

[HTML][HTML] Exo-miRNAs as a new tool for liquid biopsy in lung cancer

O Fortunato, P Gasparini, M Boeri, G Sozzi - Cancers, 2019 - mdpi.com
Lung cancer is the predominant cause of cancer-related deaths. The high mortality rates are
mainly due to the lack of diagnosis before the cancer is at a late stage. Liquid biopsy is a …

Past, present, and future of anticancer nanomedicine

K Kim, D Khang - International Journal of Nanomedicine, 2020 - Taylor & Francis
This review aims to summarize the methods that have been used till today, highlight
methods that are currently being developed, and predict the future roadmap for anticancer …

[HTML][HTML] αvβ3 Integrin induces partial EMT independent of TGF-β signaling

Y Kariya, M Oyama, T Suzuki, Y Kariya - Communications biology, 2021 - nature.com
Epithelial–mesenchymal transition (EMT) plays a pivotal role for tumor progression. Recent
studies have revealed the existence of distinct intermediate states in EMT (partial EMT); …

[HTML][HTML] Cancer-Associated Fibroblasts Promote Migration and Invasion of Non-Small Cell Lung Cancer Cells via miR-101-3p Mediated VEGFA Secretion and AKT …

X Guo, M Chen, L Cao, Y Hu, X Li, Q Zhang… - Frontiers in cell and …, 2021 - frontiersin.org
Cancer-associated fibroblasts (CAFs) are major component of tumor microenvironment
(TME), which plays crucial roles in tumor growth, invasion and metastasis; however, the …