Lung cancer is a kind of malignant tumor with rapid progression and poor prognosis. Distant
metastasis has been the main cause of mortality among lung cancer patients. Bone is one of …

Pyroptosis is an inflammation-dependent and self-cascade amplifying type of programmed
cell death, serving as an effective means for activating the local immune response and …

Abstract Background Cancer-associated fibroblasts (CAFs) in the tumour microenvironment
(TME) suppress antitumour immunity, and the tyrosine kinase inhibitor nintedanib has …

Lung cancer is a serious threat to human health with the highest morbidity and mortality;
metastatic lung cancer accounts for a majority of cancer‐related deaths. Hence, there is …

The lung is one of the most common sites for cancer metastasis. Collagens in the lung
provide a permissive microenvironment that supports the colonization and outgrowth of …

Lung cancer is the most common cause of cancer-related deaths. Lung cancers can be
classified as small-cell (SCLC) or non-small cell (NSCLC). About 84% of all lung cancers …

Background Bone is one of the common metastatic sites of lung cancer, and its prognosis is
not optimistic. We performed a study to evaluate the incidence, survival, and prognostic …

Simple Summary Persistent activation of STAT3 is frequently observed in non-small cell lung
cancer and is associated with a poor prognosis. Given the multifaceted role of STAT3 …

Organotropism during cancer metastasis occurs frequently but the underlying mechanism
remains poorly understood. Here, we show that lysosomal protein transmembrane 5 …

Pancreatic cancer lacks effective therapy. Here, we reported two metastatic pancreatic
cancer patients administrated with Claudin 18.2 (CLDN 18.2) CART therapy after the failure …