Background Routine use of whole‐cell pertussis (wP) vaccines was suspended in some
countries in the 1970s and 1980s because of concerns about adverse effects. Following this …

Background. The goal of the trial was to determine the efficacy of a multicomponent acellular
pertussis vaccine against Bordetella illnesses in comparison with a whole-cell product and …

The search for a new and improved vaccine against tuberculosis (TB) is currently a very
active field of research, which in the last 10 years has benefited tremendously from the …

Objectives: The primary objective was to assess the nature and incidence of adverse events
after a fourth dose of a tricomponent acellular pertussis-diphtheria-tetanus vaccine given in …

Acellular pertussis vaccines are less reactogenic than whole cell pertussis vaccines, but
they are also more expensive. Based on simulation models, we compared the costs and …

Pertussis (whooping cough) is a bacterial respiratory infection caused by the gram-negative
bacillus Bordetella pertussis. Its hallmark is a cough illness that lasts many weeks. A related …

To assess the safety, immunogenicity, and lot consistency of a five-component acellular
pertussis vaccine combined with diphtheria and tetanus toxoid (Connaught Laboratories …

Background Simultaneous administration of multiple vaccines to infants and children is
becoming routine. The large number of recommended childhood vaccines necessitates …

An economic evaluation was performed of universal acellular pertussis vaccination in Italy,
where until recently the overall coverage of pertussis vaccination was estimated at 50 …

The common adverse reactions associated with diphtheria, tetanus and pertussis (DTP)
vaccination are less frequent and less severe with acellular DTP (DTaP) vaccines than with …