[HTML][HTML] Advances in development and application of influenza vaccines

J Chen, J Wang, J Zhang, H Ly - Frontiers in immunology, 2021 - frontiersin.org
Influenza A virus is one of the most important zoonotic pathogens that can cause severe
symptoms and has the potential to cause high number of deaths and great economic loss …

[HTML][HTML] Animal models for influenza research: strengths and weaknesses

TQ Nguyen, R Rollon, YK Choi - Viruses, 2021 - mdpi.com
Influenza remains one of the most significant public health threats due to its ability to cause
high morbidity and mortality worldwide. Although understanding of influenza viruses has …

[HTML][HTML] The N-terminal domain of SARS-CoV-2 nsp1 plays key roles in suppression of cellular gene expression and preservation of viral gene expression

AS Mendez, M Ly, AM González-Sánchez, E Hartenian… - Cell Reports, 2021 - cell.com
Summary Nonstructural protein 1 (nsp1) is a coronavirus (CoV) virulence factor that restricts
cellular gene expression by inhibiting translation through blocking the mRNA entry channel …

[HTML][HTML] Progress in the development of universal influenza vaccines

W Sun, T Luo, W Liu, J Li - Viruses, 2020 - mdpi.com
Influenza viruses pose a significant threat to human health. They are responsible for a large
number of deaths annually and have a serious impact on the global economy. There are …

Genetic diversity, phylogeography, and evolutionary dynamics of highly pathogenic avian influenza A (H5N6) viruses

J Zhang, Y Chen, N Shan, X Wang, S Lin, K Ma… - Virus …, 2020 - academic.oup.com
From 2013 onwards, the spread of novel H5N6 highly pathogenic avian influenza (HPAI)
viruses in China has posed great threats to not only poultry industry but also human health …

[HTML][HTML] Detection and characterization of an H9N2 influenza a virus in the Egyptian Rousette Bat in Limpopo, South Africa

R Rademan, M Geldenhuys, W Markotter - Viruses, 2023 - mdpi.com
In recent years, bats have been shown to host various novel bat-specific influenza viruses,
including H17N10 and H18N11 in the Americas and the H9N2 subtype from Africa …

[HTML][HTML] Natural selection of H5N1 avian influenza a viruses with increased PA-X and NS1 shutoff activity

A Nogales, L Villamayor, S Utrilla-Trigo, J Ortego… - Viruses, 2021 - mdpi.com
Influenza A viruses (IAV) can infect a broad range of mammalian and avian species.
However, the host innate immune system provides defenses that restrict IAV replication and …

[HTML][HTML] Surveillance and characterization of avian-origin H3N2 canine influenza viruses in 2021 in China

M Chen, R Wang, Y Pei, T Zhang, Y Lyu… - One Health …, 2024 - Springer
Avian-origin H3N2 canine influenza virus (CIV) is one of the most prevalent influenza virus
subtypes in dogs worldwide. Previous studies have shown that during the evolution of H3N2 …

The influenza A virus host shutoff factor PA-X is rapidly turned over in a strain-specific manner

RE Levene, SD Shrestha, MM Gaglia - Journal of Virology, 2021 - Am Soc Microbiol
The influenza A endoribonuclease PA-X regulates virulence and transmission of the virus by
reducing host gene expression and thus regulating immune responses to influenza A virus …

Hemagglutinin affects replication, stability and airborne transmission of the H9N2 subtype avian influenza virus

X Naiqing, X Tang, X Wang, M Cai, X Liu, X Lu, S Hu… - Virology, 2024 - Elsevier
H9N2 subtype avian influenza virus (AIV) can transmit by direct as well as airborne contacts.
It has been widespread in poultry and continued to contribute to zoonotic spillover events by …