BACKGROUND Herein, we describe the consensus guideline methodology, summarize the
evidence-based recommendations we provided to the World Health Organization (WHO) for …

Evidence-based techniques have been increasingly used in the creation of clinical
guidelines and the development of recommendations for medical practice. The use of levels …

Expression of the cystic fibrosis transmembrane conductance regulator (CFTR) is altered in
individuals with the ΔF508 CFTR mutation. We previously reported differential expression of …

Background Ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR)
potentiator that improves pulmonary function in cystic fibrosis (CF) patients with at least 1 …

Filamentous fungi and yeasts are increasingly isolated from respiratory secretions of
patients with cystic fibrosis (CF), and persistent fungal colonization of the airways of such …

In 2019, it was estimated that 2.5 million people die from lower tract respiratory infections
annually. One of the main causes of these infections is Staphylococcus aureus, a bacterium …

OBJECTIVE: To review and evaluate cystic fibrosis transmembrane conductance regulator
(CFTR) modulators for the treatment of cystic fibrosis (CF). DATA SOURCES: Literature was …

Due to improved medical care, life expectancy in patients with cystic fibrosis (CF) has
veritably improved over the last decades. Importantly, cystic fibrosis related liver disease …

Cystic fibrosis (CF) is a rare autosomal-recessive disorder manifested as multisystem organ
dysfunction. The cystic fibrosis transmembrane conductance regulator (CFTR) protein …

Non-coding RNAs (ncRNAs) are an abundant class of RNAs that include small ncRNAs,
long non-coding RNAs (lncRNA) and pseudogenes. The human ncRNA atlas includes …