Dynamic changes of DNA methylation induced by benzo (a) pyrene in cancer

H Wang, B Liu, H Chen, P Xu, H Xue, J Yuan - Genes and Environment, 2023 - Springer
Abstract Benzo (a) pyrene (BaP), the earliest and most significant carcinogen among
polycyclic aromatic hydrocarbons (PAHs), has been found in foods, tobacco smoke, and …

DNA methylome perturbations: an epigenetic basis for the emergingly heritable neurodevelopmental abnormalities associated with maternal smoking and maternal …

JM Buck, L Yu, VS Knopik, JA Stitzel - Biology of Reproduction, 2021 - academic.oup.com
Maternal smoking during pregnancy is associated with an ensemble of neurodevelopmental
consequences in children and therefore constitutes a pressing public health concern …

Epigenetic dietary interventions for prevention of cancer

N Pradhan, S Kar, S Parbin, D Sengupta, M Deb… - Epigenetics of cancer …, 2019 - Elsevier
Epigenetic regulation is a dynamic and reversible process that plays an important role in the
normal development and control of gene expression in vertebrates. However, imbalances in …

Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal …

JM Buck, HC O'Neill, JA Stitzel - Epigenetics & chromatin, 2020 - Springer
Background Maternal smoking of traditional or electronic cigarettes during pregnancy, which
constitutes developmental nicotine exposure (DNE), heightens the risk of …

[HTML][HTML] Targeting the chromatin structural changes of antitumor immunity

N Li, D Lun, N Gong, G Meng, X Du, H Wang… - Journal of …, 2023 - Elsevier
Epigenomic imbalance drives abnormal transcriptional processes, promoting the onset and
progression of cancer. Although defective gene regulation generally affects carcinogenesis …

Effect of TET1 regulating MGMT on chemotherapy resistance of oral squamous cell carcinoma stem cells

W Wang, X Li, F Wang, XY Sun - Journal of Cellular …, 2018 - Wiley Online Library
The study was to evaluate the effect of ten‐eleven translocation 1 (TET1) regulating o6‐
methylguanine‐DNA methyltransferase (MGMT) in chemotherapy resistance of oral …

Developmental Nicotine Exposure Induces Intergenerational Transmission of an Ensemble of Neurodevelopmental Disorder-Like Behavioral, Neuropharmacological …

JM Buck - 2020 - search.proquest.com
Smoking during pregnancy confers liability to neurodevelopmental disorders such as ADHD,
autism, and schizophrenia in children and potentially grandchildren as well. Modeling the …

Reproduction toxicity in male mice after nitrite exposure

GAOYWZ CHANG, CLIUJGAO Xiao-qun… - Acta Anatomica …, 2017 - jpxb.bjmu.edu.cn
Objective To investigate the reproduction toxicity and molecular mechanisms in male mice
after nitrite exposure. Methods Thirty six healthy 2-month-old male mice were divided into …

Genome-wide epigenetic profiling of B cell leukemia and lymphoma

M Morsy - 2019 - gupea.ub.gu.se
Epigenetic modifications, at the level of DNA methylation and post-translational
modifications of histone tails cooperatively function in the organization of the genome, and …

亚硝酸盐暴露致雄性小鼠生殖毒性的探讨

高艳, 王志新, 常成, 刘俊, 高晓群, 邓锦波 - 解剖学报, 2017 - jpxb.bjmu.edu.cn
目的探讨亚硝酸盐暴露对雄性小鼠生殖毒性的分子机制. 方法36 只2 月龄健康雄性小鼠,
随机分为对照组(生理盐水), 低剂量组(60 mg/kg) 和高剂量组(120 mg/kg), 每组12 …