The number of publicly available parasitic worm genome sequences has increased
dramatically in the past three years, and research interest in helminth functional genomics is …

A main bottleneck in proteomics is the downstream biological analysis of highly multivariate
quantitative protein abundance data generated using mass-spectrometry-based analysis …

Aryl hydrocarbon receptor (AHR) activation by tryptophan (Trp) catabolites enhances tumor
malignancy and suppresses anti-tumor immunity. The context specificity of AHR target …

Astrocytes are glial cells that are abundant in the central nervous system (CNS) and that
have important homeostatic and disease-promoting functions. However, little is known about …

The GWAS Catalog delivers a high-quality curated collection of all published genome-wide
association studies enabling investigations to identify causal variants, understand disease …

Technological advances have enabled the profiling of multiple molecular layers at single-
cell resolution, assaying cells from multiple samples or conditions. Consequently, there is a …

Multiple sclerosis is a chronic inflammatory disease of the CNS. Astrocytes contribute to the
pathogenesis of multiple sclerosis, but little is known about the heterogeneity of astrocytes …

Formation of the three primary germ layers during gastrulation is an essential step in the
establishment of the vertebrate body plan and is associated with major transcriptional …

INTRODUCTION A complete view of human biology can only be achieved by studying the
molecular components of its smallest functional unit, the cell. Cells are internally organized …

The correct spatial distribution of proteins is vital for their function and often mis‐localization
or ectopic expression leads to diseases. For more than a decade, the Human Protein Atlas …