[HTML][HTML] Mesenchymal stromal/stem cell (MSC)-derived exosomes in clinical trials
A Lotfy, NM AboQuella, H Wang - Stem Cell Research & Therapy, 2023 - Springer
Mesenchymal stromal/stem cells (MSCs) are widely utilized in cell therapy because of their
robust immunomodulatory and regenerative properties. Their paracrine activity is one of the …
robust immunomodulatory and regenerative properties. Their paracrine activity is one of the …
Anti-inflammatory and M2 macrophage polarization-promoting effect of mesenchymal stem cell-derived exosomes
M Arabpour, A Saghazadeh, N Rezaei - International …, 2021 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent cells beneficial in regenerative medicine
and tissue repair. The therapeutic potential of MSCs for inflammatory diseases and …
and tissue repair. The therapeutic potential of MSCs for inflammatory diseases and …
[HTML][HTML] Exosome engineering: Current progress in cargo loading and targeted delivery
Exosomes, a class of small bilayer vesicles derived from virtually all eukaryotic cells, have
been exploited as a promising natural delivery platform due to their low toxicity, excellent …
been exploited as a promising natural delivery platform due to their low toxicity, excellent …
[HTML][HTML] Exosome-functionalized magnesium-organic framework-based scaffolds with osteogenic, angiogenic and anti-inflammatory properties for accelerated bone …
Y Kang, C Xu, X Dong, M Qi, D Jiang - Bioactive materials, 2022 - Elsevier
Exosomes derived from human adipose-derived stem cells (hADSCs-Exos) have shown
potential as an effective therapeutic tool for repairing bone defects. Although metal-organic …
potential as an effective therapeutic tool for repairing bone defects. Although metal-organic …
[HTML][HTML] Production, safety and efficacy of iPSC-derived mesenchymal stromal cells in acute steroid-resistant graft versus host disease: a phase I, multicenter, open …
AJC Bloor, A Patel, JE Griffin, MH Gilleece, R Radia… - Nature medicine, 2020 - nature.com
The therapeutic potential of donor-derived mesenchymal stromal cells (MSCs) has been
investigated in diverse diseases, including steroid-resistant acute graft versus host disease …
investigated in diverse diseases, including steroid-resistant acute graft versus host disease …
[HTML][HTML] Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms
R Zhu, T Yan, Y Feng, Y Liu, H Cao, G Peng, Y Yang… - Cell research, 2021 - nature.com
The infusion of coronavirus disease 2019 (COVID-19) patients with mesenchymal stem cells
(MSCs) potentially improves clinical symptoms, but the underlying mechanism remains …
(MSCs) potentially improves clinical symptoms, but the underlying mechanism remains …
[HTML][HTML] Role of exosomes in the pathogenesis, diagnosis, and treatment of central nervous system diseases
Y Fan, Z Chen, M Zhang - Journal of Translational Medicine, 2022 - Springer
Central nervous system (CNS) diseases, such as multiple sclerosis, Alzheimer's disease
(AD), and Parkinson's disease (PD), affect millions of people around the world. Great efforts …
(AD), and Parkinson's disease (PD), affect millions of people around the world. Great efforts …
[HTML][HTML] Atherosclerosis and inflammation: insights from the theory of general pathological processes
E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …
[HTML][HTML] Targeted delivery of neural progenitor cell-derived extracellular vesicles for anti-inflammation after cerebral ischemia
T Tian, L Cao, C He, Q Ye, R Liang, W You, H Zhang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Ischemic stroke remains a major cause of death, and anti-inflammatory strategies hold great
promise for preventing major brain injury during reperfusion. In the past decade, stem cell …
promise for preventing major brain injury during reperfusion. In the past decade, stem cell …
Generation of small RNA-modulated exosome mimetics for bone regeneration
Administration of exosomes is considered an attractive cell-free approach to skeletal repair
and pathological disease treatment. However, poor yield for the production technique and …
and pathological disease treatment. However, poor yield for the production technique and …