Since the dawn of time, or at least the dawn of recombinant DNA technology (which for many
of today's scientists is the same thing), investigators have been cloning and expressing …

Fusion expression is a common practice for recombinant protein production. Some fusion
tags confer solubility on the target protein whereas others provide affinity handles that …

Molecules that covalently bind macromolecular targets have found widespread applications
as activity-based probes and as irreversibly binding drugs. However, the general reactivity of …

Both Traditional Students and Working Professionals Acquire the Skills to Analyze Social
Problems. Big Data and Social Science: A Practical Guide to Methods and Tools shows how …

Phages are increasingly recognized as important members of host-associated microbiomes,
with a vast genomic diversity. The new frontier is to understand how phages may affect …

The N-glycans attached to the Fab and Fc domains play distinct roles in modulating the
functions of antibodies. However, posttranslational site-selective modifications of glycans in …

Glycosylation can exert a profound impact on the structures and biological functions of
antibodies. Glycosylation remodeling using the endoglycosidase-catalyzed deglycosylation …

Perilipins (PLINs) play a key role in energy storage by orchestrating the activity of lipases on
the surface of lipid droplets. Failure of this activity results in severe metabolic disease in …

Pathogenic microbes are known to manipulate the defences of their hosts through the
production of secreted effector proteins. More recently, mutualistic mycorrhizal fungi have …

Chemoenzymatic synthesis is emerging as a promising approach to the synthesis of
homogeneous glycopeptides and glycoproteins highly demanded for functional glycomics …