[HTML][HTML] The aging gut microbiome and its impact on host immunity

N Bosco, M Noti - Genes & Immunity, 2021 - nature.com
The microbiome plays a fundamental role in the maturation, function, and regulation of the
host-immune system from birth to old age. In return, the immune system has co-evolved a …

[HTML][HTML] Home as the new frontier for the treatment of COVID-19: the case for anti-inflammatory agents

N Perico, M Cortinovis, F Suter… - The Lancet Infectious …, 2023 - thelancet.com
Summary COVID-19, caused by SARS-CoV-2, is characterised by a broad spectrum of
symptom severity that requires varying amounts of care according to the different stages of …

[HTML][HTML] Non-steroidal anti-inflammatory drugs: Recent advances in the use of synthetic COX-2 inhibitors

M Ahmadi, S Bekeschus, KD Weltmann… - RSC Medicinal …, 2022 - pubs.rsc.org
Cyclooxygenase (COX) enzymes comprise COX-1 and COX-2 isoforms and are responsible
for prostaglandin production. Prostaglandins have critical roles in the inflammation pathway …

[HTML][HTML] Inhibition of the main protease of SARS-CoV-2 (Mpro) by repurposing/designing drug-like substances and utilizing nature's toolbox of bioactive compounds

I Antonopoulou, E Sapountzaki, U Rova… - Computational and …, 2022 - Elsevier
The emergence of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)
has resulted in a long pandemic, with numerous cases and victims worldwide and enormous …

[HTML][HTML] Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease

M Ricke-Hoch, E Stelling, L Lasswitz, AP Gunesch… - PloS one, 2021 - journals.plos.org
The SARS-CoV-2 coronavirus has led to a pandemic with millions of people affected. The
present study finds that risk-factors for severe COVID-19 disease courses, ie male sex, older …

Drug safety of frequently used drugs and substances for self-medication in COVID-19

D Baracaldo-Santamaría… - … advances in drug …, 2022 - journals.sagepub.com
During the COVID-19 pandemic, the behavior of self-medication has increased. The
dissemination of misleading information regarding the efficacy of certain drugs or …

[HTML][HTML] The find of COVID-19 vaccine: Challenges and opportunities

M ElBagoury, MM Tolba, HA Nasser, A Jabbar… - Journal of infection and …, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus (SARS-CoV-2), a novel corona virus,
causing COVID-19 with Flu-like symptoms is the first alarming pandemic of the third …

[HTML][HTML] Коронавирусная болезнь 2019 (COVID-19) и иммуновоспалительные ревматические заболевания. Рекомендации Общероссийской общественной …

ЕЛ Насонов, АМ Лила, ВИ Мазуров… - Научно …, 2021 - cyberleninka.ru
В середине 2021 года инфекция SARS-CoV-2 (Severe Acute Respiratory coronavirus 2),
вызвавшая пандемию коронавирусной болезни 2019 (coronavirus disease, COVID-19) …

[HTML][HTML] A simple, home-therapy algorithm to prevent hospitalisation for COVID-19 patients: A retrospective observational matched-cohort study

F Suter, E Consolaro, S Pedroni, C Moroni… - …, 2021 - thelancet.com
Background Effective home treatment algorithms implemented based on a pathophysiologic
and pharmacologic rationale to accelerate recovery and prevent hospitalisation of patients …

[HTML][HTML] Activated platelets facilitate hematogenous metastasis of breast cancer by modulating the PDGFR-β/COX-2 axis

Y Tang, C Qian, Y Zhou, C Yu, M Song, T Zhang, X Min… - IScience, 2023 - cell.com
Platelets have been widely recognized as a bona fide mediator of malignant diseases, and
they play significant roles in influencing various aspects of tumor progression. Paracrine …