Neurotransmitter systems in the etiology of major neurological disorders: Emerging insights and therapeutic implications
Neurotransmitters serve as chemical messengers playing a crucial role in information
processing throughout the nervous system, and are essential for healthy physiological and …
processing throughout the nervous system, and are essential for healthy physiological and …
Anticholinergics: theoretical and clinical overview
PS Nishtala, MS Salahudeen… - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: Anticholinergics are a class of medicines that block the neurotransmitter,
acetylcholine, in the brain and peripheral tissues. Medicines with anticholinergic activity are …
acetylcholine, in the brain and peripheral tissues. Medicines with anticholinergic activity are …
[HTML][HTML] The pathobiology of myalgic encephalomyelitis/chronic fatigue syndrome: the case for neuroglial failure
H Renz-Polster, ME Tremblay, D Bienzle… - Frontiers in cellular …, 2022 - frontiersin.org
Although myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) has a specific and
distinctive profile of clinical features, the disease remains an enigma because causal …
distinctive profile of clinical features, the disease remains an enigma because causal …
Anticholinergic medication: related dry mouth and effects on the salivary glands
S Arany, DT Kopycka-Kedzierawski, TV Caprio… - Oral surgery, oral …, 2021 - Elsevier
Objective Salivary glands are among the most sensitive target organs of medications with
anticholinergic (AC) properties, interrupting the neural stimulation of saliva secretion and …
anticholinergic (AC) properties, interrupting the neural stimulation of saliva secretion and …
Dysfunction in brain-derived neurotrophic factor signaling pathway and susceptibility to schizophrenia, Parkinson's and Alzheimer's diseases
A Mohammadi, VG Amooeian… - Current gene …, 2018 - ingentaconnect.com
Brain-Derived Neurotrophic Factor (BDNF) is a dominant neurotrophic factor in the brain
which plays a crucial role in differentiation, regeneration and plasticity mechanisms. Binding …
which plays a crucial role in differentiation, regeneration and plasticity mechanisms. Binding …
Gi/o-Protein Coupled Receptors in the Aging Brain
PG de Oliveira, MLS Ramos, AJ Amaro… - Frontiers in aging …, 2019 - frontiersin.org
Cells translate extracellular signals to regulate processes such as differentiation,
metabolism and proliferation, via transmembranar receptors. G protein-coupled receptors …
metabolism and proliferation, via transmembranar receptors. G protein-coupled receptors …
G protein-coupled receptors in neurodegenerative diseases and psychiatric disorders
Neuropsychiatric disorders are multifactorial disorders with diverse aetiological factors.
Identifying treatment targets is challenging because the diseases are resulting from …
Identifying treatment targets is challenging because the diseases are resulting from …
Anticholinergic drug burden in older people's brain–how well is it measured?
H Kersten, TB Wyller - Basic & clinical pharmacology & …, 2014 - Wiley Online Library
Concurrent use of several drugs with potential anticholinergic properties is highly prevalent
in the elderly. Methods to determine the overall anticholinergic drug burden have been …
in the elderly. Methods to determine the overall anticholinergic drug burden have been …
Small vessel disease to subcortical dementia: a dynamic model, which interfaces aging, cholinergic dysregulation and the neurovascular unit
P Caruso, R Signori, R Moretti - Vascular health and risk …, 2019 - Taylor & Francis
Background Small vessels have the pivotal role for the brain's autoregulation. The
arteriosclerosis-dependent alteration of the brain perfusion is one of the major determinants …
arteriosclerosis-dependent alteration of the brain perfusion is one of the major determinants …
Quercetin protects the impairment of memory and anxiogenic-like behavior in rats exposed to cadmium: Possible involvement of the acetylcholinesterase and Na+, K+ …
The present study investigated the effects of quercetin in the impairment of memory and
anxiogenic-like behavior induced by cadmium (Cd) exposure. We also investigated possible …
anxiogenic-like behavior induced by cadmium (Cd) exposure. We also investigated possible …