Onchocerciasis is a parasitic infection caused by the filarial nematode Onchocerca volvulus
and transmitted through the bites of black flies of the genus Similium that breed in rivers and …

Objective: Altered glutamatergic neurotransmission is implicated in the pathogenesis of
major depressive disorder. AXS-05 (dextromethorphan-bupropion) is an oral NMDA …

Background: Onchocerciasis (river blindness), caused by the filarial worm species
Onchocerca volvulus, is a serious vector-borne neglected tropical disease (NTD) of public …

Background Surveys conducted in 1991–1992 in the Mbam Valley (Cameroon) revealed
that onchocerciasis was highly endemic, with community microfilarial loads (CMFL)> 100 …

Background Serological assessments for human onchocerciasis are based on IgG4
reactivity against the OV-16 antigen, with sensitivities of 60-80%. We have previously …

There is greater than tenfold variation in nephron number of the human kidney at birth.
Although low nephron number is a recognized risk factor for CKD, its determinants are …

Abstract Background The World Health Organization recommends monitoring Onchocerca
volvulus Ov16 serology in children aged< 10 years for stopping mass ivermectin …

Understanding when it is the appropriate time to stop administering the drugs in a
chemotherapy-centered treatment program such as onchocerciasis remains a challenge …

Recently, there were anecdotal reports of a high number of persons with epilepsy, including
children with nodding seizures in the Landja Mboko area located about 9 km from the capital …

While many public health and university laboratories have become involved in COVID-19
testing during the pandemic, these same laboratories now run the risk of being underutilized …