A non-coding genetic variant associated with abdominal aortic aneurysm alters ERG gene regulation

J Marsman, G Gimenez, RC Day… - Human molecular …, 2020 - academic.oup.com
Abdominal aortic aneurysm (AAA) is a major cause of sudden death in the elderly. While
AAA has some overlapping genetic and environmental risk factors with atherosclerosis …

The association of ANRIL with Coronary Artery Disease and aortic aneurysms, how far does the gene desert go?

WC Ng, J Chan, TN Tarkas, N Meharban… - Annals of Vascular …, 2022 - Elsevier
Background Coronary artery disease (CAD) and aortic aneurysms (AA) are 2 cardiovascular
diseases that share a multifactorial aetiology. The influence of family history and genetics on …

Mycotic aneurysm secondary to melioidosis in China: a series of eight cases and a review of literature

H Wu, X Wang, X Zhou, Z Wu, Y Wang… - PLoS Neglected …, 2020 - journals.plos.org
Burkholderia pseudomallei is the causative agent of melioidosis, endemic in Southeast Asia
and Northern Australia, and increasingly recognized in southern China, especially in Hainan …

Disintegrin and metalloproteinases (ADAMs [a disintegrin and metalloproteinase] and ADAMTSs [ADAMs with a thrombospondin motif]) in aortic aneurysm

T Kilic, K Okuno, S Eguchi, Z Kassiri - Hypertension, 2022 - Am Heart Assoc
Aortic aneurysm is a complex pathology that can be lethal if not detected in time. Although
several molecular mechanisms and pathways have been identified to be involved in aortic …

Application and challenges of TCR and BCR sequencing to investigate T-and B-cell clonality in elastase-induced experimental murine abdominal aortic aneurysm

C Elster, M Ommer-Bläsius, A Lang, T Vajen… - Frontiers in …, 2023 - frontiersin.org
Background An abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular
disease. Although its pathogenesis is still poorly understood, recent evidence suggests that …

Weighted gene co-expression network analysis reveals key genes and potential drugs in abdominal aortic aneurysm

KJ Kan, F Guo, L Zhu, P Pallavi, M Sigl, M Keese - Biomedicines, 2021 - mdpi.com
Abdominal aortic aneurysm (AAA) is a prevalent aortic disease that causes high mortality
due to asymptomatic gradual expansion and sudden rupture. The underlying molecular …

Early detection of undiagnosed abdominal aortic aneurysm and sub-aneurysmal aortic dilatations in patients with high-risk coronary artery disease: The value of …

ST Saw, BDK Leong, DA Abdul Aziz - Vascular health and risk …, 2020 - Taylor & Francis
Introduction Abdominal aortic aneurysm (AAA) and coronary artery disease (CAD) share
common risk factors. The objective of this study was to determine the prevalence of …

Systems approach to study associations between OxLDL and abdominal aortic aneurysms

Ł Gutowski, K Gutowska… - International Journal of …, 2019 - mdpi.com
Although abdominal aortic aneurysm (AAA) is a common vascular disease and is associated
with high mortality, the full pathogenesis of AAA remains unknown to researchers …

[HTML][HTML] Incorporating machine learning and PPI networks to identify mitochondrial fission-related immune markers in abdominal aortic aneurysms

Y Liu, R Li, D Xiao, C Yang, Y Li, J Chen, Z Wang… - Heliyon, 2024 - cell.com
Purpose The aim of this study is to investigate abdominal aortic aneurysm (AAA), a disease
characterised by inflammation and progressive vasodilatation, for novel gene-targeted …

Comprehensive transcriptomic analysis unveils macrophage-associated genes for establishing an abdominal aortic aneurysm diagnostic model and molecular …

Z Wu, W Yu, J Luo, G Shen, Z Cui, W Ni… - European Journal of …, 2024 - Springer
Background Abdominal aortic aneurysm (AAA) is a highly lethal cardiovascular disease. The
aim of this research is to identify new biomarkers and therapeutic targets for the treatment of …