The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives
C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …
[HTML][HTML] Quorum sensing: A less known mode of communication among fungi
SA Padder, R Prasad, AH Shah - Microbiological research, 2018 - Elsevier
Quorum sensing (QS), a density-dependent signaling mechanism of microbial cells, involves
an exchange and sense of low molecular weight signaling compounds called autoinducers …
an exchange and sense of low molecular weight signaling compounds called autoinducers …
[HTML][HTML] Infection of fungi and bacteria in brain tissue from elderly persons and patients with Alzheimer's disease
R Alonso, D Pisa, AM Fernández-Fernández… - Frontiers in aging …, 2018 - frontiersin.org
Alzheimer's disease (AD) is the leading cause of dementia in elderly people. The etiology of
this disease remains a matter of intensive research in many laboratories. We have advanced …
this disease remains a matter of intensive research in many laboratories. We have advanced …
[HTML][HTML] Time to conquer fungal infectious diseases: employing nanoparticles as powerful and versatile antifungal nanosystems against a wide variety of fungal …
The development of novel antifungal agents and, in particular, the widespread use of these
medications over the course of the past two decades, has had a significant impact on the …
medications over the course of the past two decades, has had a significant impact on the …
[HTML][HTML] Fungal pigments and their roles associated with human health
L Lin, J Xu - Journal of Fungi, 2020 - mdpi.com
Fungi can produce myriad secondary metabolites, including pigments. Some of these
pigments play a positive role in human welfare while others are detrimental. This paper …
pigments play a positive role in human welfare while others are detrimental. This paper …
Emergence and evolution of virulence in human pathogenic fungi
One billion people worldwide are affected by fungal pathogens, of which 1.6 million
succumb to fungal infections per year. This review discusses the emergence and evolution …
succumb to fungal infections per year. This review discusses the emergence and evolution …
[HTML][HTML] Checkpoint inhibitors as immunotherapy for fungal infections: Promises, challenges, and unanswered questions
Opportunistic fungal infections have high mortality in patients with severe immune
dysfunction. Growing evidence suggests that the immune environment of invasive fungal …
dysfunction. Growing evidence suggests that the immune environment of invasive fungal …
[HTML][HTML] Immune intervention in sepsis
J Chen, H Wei - Frontiers in Pharmacology, 2021 - frontiersin.org
Sepsis is a host immune disorder induced by infection. It can lead to multiple organ
dysfunction syndrome (MODS), which has high morbidity and mortality. There has been …
dysfunction syndrome (MODS), which has high morbidity and mortality. There has been …
[HTML][HTML] Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion
A Pradhan, GM Avelar, JM Bain, D Childers… - Nature …, 2019 - nature.com
To colonise their host, pathogens must counter local environmental and immunological
challenges. Here, we reveal that the fungal pathogen Candida albicans exploits diverse host …
challenges. Here, we reveal that the fungal pathogen Candida albicans exploits diverse host …
PAMPs of the fungal cell wall and mammalian PRRs
Fungi are opportunistic pathogens that infect immunocompromised patients and are
responsible for an estimated 1.5 million deaths every year. The antifungal innate immune …
responsible for an estimated 1.5 million deaths every year. The antifungal innate immune …