[HTML][HTML] Application of approved cisplatin derivatives in combination therapy against different cancer diseases
D Tsvetkova, S Ivanova - Molecules, 2022 - mdpi.com
The problems with anticancer therapy are resistance and toxicity. From 3000 Cisplatin
derivatives tested as antitumor agents, most of them have been rejected, due to toxicity. The …
derivatives tested as antitumor agents, most of them have been rejected, due to toxicity. The …
Understanding structure–function relationships of nanoadjuvants for enhanced cancer vaccine efficacy
J Tan, B Ding, B Teng, P Ma… - Advanced Functional …, 2022 - Wiley Online Library
Adjuvant, as an important part of vaccines, can observably enhance the magnitude, breadth
and durability of immune responses. Nanoadjuvants, as novel vaccine adjuvants, have …
and durability of immune responses. Nanoadjuvants, as novel vaccine adjuvants, have …
[HTML][HTML] Complement and coagulation cascades pathway-related signature as a predictor of immunotherapy in metastatic urothelial cancer
Z Gong, Y He, X Mi, C Li, X Sun, G Wang, L Li… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Background: Immune checkpoint inhibitors (ICIs) have shown efficacy in patients with
metastatic urothelial cancer (mUC), however, only a small subset of patients could benefit …
metastatic urothelial cancer (mUC), however, only a small subset of patients could benefit …
[HTML][HTML] Complement system: an immunotherapy target in colorectal cancer
Colorectal cancer (CRC) is the third most common malignant tumor and the second most
fatal cancer worldwide. Several parts of the immune system contribute to fighting cancer …
fatal cancer worldwide. Several parts of the immune system contribute to fighting cancer …
[HTML][HTML] Cancer-associated stromal fibroblast-derived transcriptomes predict poor clinical outcomes and immunosuppression in colon cancer
J Wang, R Akter, MF Shahriar… - Pathology and Oncology …, 2022 - por-journal.com
Background: Previous studies revealed that colonic cancer-associated fibroblasts (CAFs)
are associated with the modulation of the colon tumor microenvironment (TME). However …
are associated with the modulation of the colon tumor microenvironment (TME). However …
[HTML][HTML] Leptomeningeal disease (LMD) in patients with melanoma metastases
Simple Summary Leptomeningeal disease in melanoma (LMM) patients is characterized by
aggressiveness and dismal outcomes. Clinical studies and case reports demonstrate the …
aggressiveness and dismal outcomes. Clinical studies and case reports demonstrate the …
[HTML][HTML] Immunotherapy: A new target for cancer cure
F Zhao, D Shen, M Shang, H Yu, X Zuo… - Oncology …, 2023 - spandidos-publications.com
Cancer is the leading cause of death globally and there is a worldwide cancer epidemic.
Immunotherapy has emerged as a promising anticancer therapy. In particular, oncolytic …
Immunotherapy has emerged as a promising anticancer therapy. In particular, oncolytic …
Leptomeningeal metastasis in ER+ HER2-advanced breast cancer patients: a review of the cases in a single institute over a 15-year period
J Watanabe, K Mitsuya, S Nakamoto, H Harada… - Breast Cancer Research …, 2021 - Springer
Purpose While leptomeningeal metastasis (LM) from estrogen receptor-positive, HER2-
negative advanced breast cancer (ER+ HER2-ABC) has a poor prognosis, the details of …
negative advanced breast cancer (ER+ HER2-ABC) has a poor prognosis, the details of …
[HTML][HTML] Application of proteomics in the discovery of radiosensitive cancer biomarkers
H Luo, H Ge - Frontiers in Oncology, 2022 - frontiersin.org
Radiation therapy remains an important component of cancer treatment. Gene-encoded
proteins were the actual executors of cellular functions. Proteomic was a novel technology …
proteins were the actual executors of cellular functions. Proteomic was a novel technology …
[HTML][HTML] Components of the lectin pathway of complement in solid tumour cancers
M Cedzyński, AS Świerzko - Cancers, 2022 - mdpi.com
Simple Summary Cancer is a major cause of human deaths. The complement system is an
important branch of the innate immune response that can be activated via three distinct …
important branch of the innate immune response that can be activated via three distinct …