Clarification of the definition of hypoplastic left heart syndrome

RH Anderson, DE Spicer, A Crucean - Nature Reviews Cardiology, 2021 - nature.com
There is still no consensus on the anatomical combinations that make up the so-called
hypoplastic left heart syndrome. We argue that an intact ventricular septum should now be …

The left ventricular myocardium in hypoplastic left heart syndrome

B Chaudhry, A Alqahtani, L Eley, L Coats… - Journal of …, 2022 - mdpi.com
Hypoplastic left heart syndrome (HLHS) is a collective term applied to severe congenital
cardiac malformations, characterised by a combination of abnormalities mainly affecting the …

A mouse model of hypoplastic left heart syndrome demonstrating left heart hypoplasia and retrograde aortic arch flow

A Rahman, T DeYoung, LS Cahill… - Disease Models & …, 2021 - journals.biologists.com
In hypoplastic left heart syndrome (HLHS), the mechanisms leading to left heart hypoplasia
and their associated fetal abnormalities are largely unknown. Current animal models have …

Combined hybrid procedure and VAD insertion in 9 high-risk neonates and infants with HLHS

MS Bleiweis, J Philip, GJ Peek, JC Fudge… - The Annals of Thoracic …, 2022 - Elsevier
Background This report describes 9 high-risk neonates and infants with hypoplastic left heart
syndrome (HLHS) who were stabilized with a combined hybrid approach and ventricular …

A “holistic” sonographic view on congenital heart disease: How automatic reconstruction using fetal intelligent navigation echocardiography eases unveiling of …

J Weichert, A Weichert - Echocardiography, 2021 - Wiley Online Library
Volume ultrasound has been shown to provide valid complementary information on fetal
anatomy. Four‐dimensional assessment (4D) of the fetal cardiovascular system using …

Which Phenotypes Should We Include in the Hypoplastic Left Heart Syndrome?

RH Anderson, DE Spicer… - World Journal for …, 2023 - journals.sagepub.com
The recent special issue of the World Journal for Pediatric and Congenital Heart Surgery
devoted to hypoplastic left heart syndrome, and its related anomalies, contained significant …

The morphogenesis of abnormal coronary arteries in the congenitally malformed heart

RH Anderson, JE Turner, DJ Henderson - The Journal of Thoracic and …, 2022 - jtcvs.org
Feature Editor Note—The relentless work of evolution has resulted in well-formed coronary
arteries. The normal and abnormal development of the coronary arteries is one of the most …

[HTML][HTML] Single-cell RNA sequencing and quantitative proteomics analysis elucidate marker genes and molecular mechanisms in hypoplastic left heart patients with …

L Ma, N Zhou, R Zou, W Shi, Y Luo, N Du… - Frontiers in Cell and …, 2021 - frontiersin.org
Objective To probe markers and molecular mechanisms of the hypoplastic left heart (HLH)
by single-cell RNA sequencing (scRNA-seq) and quantitative proteomics analysis. Methods …

Flow-mediated factors in the pathogenesis of hypoplastic left heart syndrome

A Rahman, RR Chaturvedi, JG Sled - Journal of Cardiovascular …, 2022 - mdpi.com
Hypoplastic left heart syndrome (HLHS) is a life-threatening congenital heart disease that is
characterized by severe underdevelopment of left heart structures. Currently, there is no …

Reply to Nezic

M Czerny, M Feisst - European Journal of Cardio-Thoracic …, 2021 - academic.oup.com
I read with great interest the article by Czerny et al.[1], which aimed to create a web-based
application for the prediction of the 30-day mortality rate for patients undergoing surgery for …