Clostridioides difficile, a New “Superbug”

R Markovska, G Dimitrov, R Gergova, L Boyanova - Microorganisms, 2023 - mdpi.com
Clostridioides difficile is a Gram-positive, spore-forming, anaerobic bacterium. The clinical
features of C. difficile infections (CDIs) can vary, ranging from the asymptomatic carriage and …

Genomic Delineation of Zoonotic Origins of Clostridium difficile

DR Knight, TV Riley - Frontiers in public health, 2019 - frontiersin.org
Clostridium difficile is toxin-producing antimicrobial resistant (AMR) enteropathogen
historically associated with diarrhea and pseudomembranous colitis in hospitalized patients …

An environmental cleaning bundle and health-care-associated infections in hospitals (REACH): a multicentre, randomised trial

BG Mitchell, L Hall, N White, AG Barnett… - The lancet infectious …, 2019 - thelancet.com
Background The hospital environment is a reservoir for the transmission of microorganisms.
The effect of improved cleaning on patient-centred outcomes remains unclear. We aimed to …

Evolutionary and Genomic Insights into Clostridioides difficile Sequence Type 11: a Diverse Zoonotic and Antimicrobial-Resistant Lineage of Global One Health …

DR Knight, B Kullin, GO Androga, F Barbut, C Eckert… - MBio, 2019 - Am Soc Microbiol
Clostridioides difficile (Clostridium difficile) sequence type 11 (ST11) is well established in
production animal populations worldwide and contributes considerably to the global burden …

Global prevalence of Clostridioides difficile in 17,148 food samples from 2009 to 2019: a systematic review and meta-analysis

S Borji, S Kadivarian, S Dashtbin, S Kooti… - Journal of Health …, 2023 - Springer
Abstract Background Clostridioides (Clostridium) difficile is an important infectious
pathogen, which causes mild-to-severe gastrointestinal infections by creating resistant …

The Environment, Farm Animals and Foods as Sources of Clostridioides difficile Infection in Humans

D Bolton, P Marcos - Foods, 2023 - mdpi.com
The recent discovery of the same Clostridioides difficile ribotypes associated with human
infection in a broad range of environments, animals and foods, coupled with an ever …

Detection and Genomic Characterisation of Clostridioides difficile from Spinach Fields

P Marcos, P Whyte, C Burgess, D Ekhlas, D Bolton - Pathogens, 2022 - mdpi.com
Despite an increased incidence of Clostridioides difficile infections, data on the reservoirs
and dissemination routes of this bacterium are limited. This study examined the prevalence …

One health perspectives on food safety in minimally processed vegetables and fruits: From farm to fork

MI Santos, M Grácio, MC Silva, L Pedroso, A Lima - Microorganisms, 2023 - mdpi.com
While food markets and food production chains are experiencing exponential growth, global
attention to food safety is steadily increasing. This is particularly crucial for ready-to-eat …

Whole‐genome sequencing links Clostridium (Clostridioides) difficile in a single hospital to diverse environmental sources in the community

SC Lim, DA Collins, K Imwattana… - Journal of applied …, 2022 - academic.oup.com
Abstract Aims To investigate if Clostridium (Clostridioides) difficile infection (CDI),
traditionally thought of as hospital‐acquired, can be genomically linked to hospital or …

Make It Less difficile: Understanding Genetic Evolution and Global Spread of Clostridioides difficile

M Mengoli, M Barone, M Fabbrini, F D'Amico, P Brigidi… - Genes, 2022 - mdpi.com
Clostridioides difficile is an obligate anaerobic pathogen among the most common causes of
healthcare-associated infections. It poses a global threat due to the clinical outcomes of …