Safety and efficacy of responsive neurostimulation in the pediatric population: evidence from institutional review and patient-level meta-analysis
P Kerezoudis, A Gyftopoulos, AY Alexander… - Epilepsy & Behavior, 2022 - Elsevier
Background Responsive neurostimulation (RNS) is a novel technology for drug-resistant
epilepsy rising from bilateral hemispheres or eloquent cortex. Although recently approved …
epilepsy rising from bilateral hemispheres or eloquent cortex. Although recently approved …
Real-world preliminary experience with responsive neurostimulation in pediatric epilepsy: a multicenter retrospective observational study
Y Nagahama, TM Zervos, KK Murata, L Holman… - …, 2021 - journals.lww.com
Real-World Preliminary Experience With Responsive Neurostimu... : Neurosurgery Real-World
Preliminary Experience With Responsive Neurostimulation in Pediatric Epilepsy: A …
Preliminary Experience With Responsive Neurostimulation in Pediatric Epilepsy: A …
Closed-loop stimulation in periods with less epileptiform activity drives improved epilepsy outcomes
In patients with drug-resistant epilepsy, electrical stimulation of the brain in response to
epileptiform activity can make seizures less frequent and debilitating. This therapy, known as …
epileptiform activity can make seizures less frequent and debilitating. This therapy, known as …
Pathway of transient electronics towards connected biomedical applications
Transient electronic devices have shown promising applications in hardware security and
medical implants with diagnosing therapeutics capabilities since their inception. Control of …
medical implants with diagnosing therapeutics capabilities since their inception. Control of …
Elevated basal glutamate and unchanged glutamine and GABA in refractory epilepsy: Microdialysis study of 79 patients at the yale epilepsy surgery program
I Çavuş, JC Romanyshyn, JT Kennard… - Annals of …, 2016 - Wiley Online Library
Objective Aberrant glutamate and γ‐aminobutyric acid (GABA) neurotransmission contribute
to seizure generation and the epileptic state. However, whether levels of these …
to seizure generation and the epileptic state. However, whether levels of these …
Network connectivity predicts effectiveness of responsive neurostimulation in focal epilepsy
JM Fan, AT Lee, K Kudo, KG Ranasinghe… - Brain …, 2022 - academic.oup.com
Responsive neurostimulation is a promising treatment for drug-resistant focal epilepsy;
however, clinical outcomes are highly variable across individuals. The therapeutic …
however, clinical outcomes are highly variable across individuals. The therapeutic …
[HTML][HTML] Responsive neurostimulation targeting the anterior, centromedian and pulvinar thalamic nuclei and the detection of electrographic seizures in pediatric and …
Background: Responsive neurostimulation (RNS System) has been utilized as a treatment
for intractable epilepsy. The RNS System delivers stimulation in response to detected …
for intractable epilepsy. The RNS System delivers stimulation in response to detected …
Treatment of medically refractory seizures with responsive neurostimulation: 2 pediatric cases
MA Kokoszka, F Panov, M La Vega-Talbott… - Journal of …, 2018 - thejns.org
The responsive neurostimulation (RNS) system, an adjunctive treatment for
pharmacoresistant partial-onset seizures with 1 or 2 foci, has been available to patients …
pharmacoresistant partial-onset seizures with 1 or 2 foci, has been available to patients …
Treatment for loss of control disorders
The present invention provides, inter alia, methods, apparatus, and systems useful for
ameliorating impulse control disorders known to be extremely disabling and common to …
ameliorating impulse control disorders known to be extremely disabling and common to …
Optogenetic stimulation reveals a latent tipping point in cortical networks during ictogenesis
RT Graham, RR Parrish, L Alberio, EL Johnson… - Brain, 2023 - academic.oup.com
Brain-state transitions are readily apparent from changes in brain rhythms, but are difficult to
predict, suggestive that the underlying cause is latent to passive recording methods. Among …
predict, suggestive that the underlying cause is latent to passive recording methods. Among …