[HTML][HTML] Evaluation of polymer nanoformulations in hepatoma therapy by established rodent models

Q Wang, P Zhang, Z Li, X Feng, C Lv, H Zhang… - Theranostics, 2019 - ncbi.nlm.nih.gov
Hepatoma is one of the most severe malignancies usually with poor prognosis, and many
patients are insensitive to the existing therapeutic agents, including the drugs for …

Synthesis of albumin nanoparticles in a water-miscible ionic liquid system, and their applications for chlorambucil delivery to cancer cells

Y Akdogan, SC Sozer, C Akyol, M Basol… - Journal of Molecular …, 2022 - Elsevier
Serum albumin has been a preferred protein to generate biodegradable and non-toxic
nanoparticles (NPs) for drug delivery applications. Different methods applied for the …

[HTML][HTML] Fabrication of chlorambucil loaded graphene-oxide nanocarrier and its application for improved antitumor activity

G Singh, BP Nenavathu, K Imtiyaz… - Biomedicine & …, 2020 - Elsevier
The present study aims at designing a biodegradable and biocompatible nanocarrier using
gelatin and reduced graphene oxide nanosheets functionalized with folic acid, for release of …

Rhodamine B-Conjugated Fluorescent Block Copolymer Micelles for Efficient Chlorambucil Delivery and Intracellular Imaging

B Kulkarni, S Qutub, NM Khashab, N Hadjichristidis - ACS omega, 2023 - ACS Publications
The clinical development of the anticancer drug chlorambucil (CHL) is limited by its low
solubility in water, poor bioavailability, and off-target toxicity. Besides, another constraint for …

Evaluation of photodynamic activity, photostability and in vitro drug release of zinc phthalocyanine-loaded nanocapsules

TD de Souza, FI Ziembowicz, DF Mueller… - European journal of …, 2016 - Elsevier
Nanocapsule formulations containing zinc phthalocyanine (ZnPc) were investigated as drug
delivery systems for use in photodynamic therapy (PDT). ZnPc loaded chitosan, PCL, and …

Chlorambucil-iron oxide nanoparticles as a drug delivery system for leukemia cancer cells

SH Hussein-Al-Ali, MZ Hussein, S Bullo… - International journal of …, 2021 - Taylor & Francis
Introduction Traditional cancer therapies may have incomplete eradication of cancer or
destroy the normal cells. Nanotechnology solves the demerit by a guide in surgical resection …

Tumor Targeting by Conjugation of Chlorambucil with Zwitterionic Near-Infrared Fluorophore for Cancer Phototherapy

G Jo, EJ Kim, H Hyun - International Journal of Molecular Sciences, 2022 - mdpi.com
Improving the tumor targeting of anticancer drugs to minimize systemic exposure remains
challenging. The chemical conjugation of anticancer drugs with various near-infrared (NIR) …

[PDF][PDF] Chlorambucil encapsulation into PLGA nanoparticles and cytotoxic effects in breast cancer cell.

DJS Dias, GA Joanitti, RB Azevedo, LP Silva… - 2015 - alice.cnptia.embrapa.br
The present work aimed to develop and evaluate a colloidal system composed of poly (DL-
lactideco-glycolide)(PLGA) nanoparticles (NPs) associated with chlorambucil (CHB) and its …

Effect of solvents on forming poly (butyl-2-cyanoacrylate) encapsulated paeonol nanocapsules

J Yao, D Zeng, Y Zhang, D Sun, E Yang… - Journal of …, 2017 - Taylor & Francis
The effect of ethanol or acetone, as oil phase solvents, upon the form of paeonol-loaded
poly (butyl-2-cyanoacrylate) encapsulated nanocapsules (Pae@ PNCs) by interfacial …

Influence of the preparation method on the physicochemical properties of econazole-loaded poly (butyl cyanoacrylate) colloidal nanoparticles

G Yordanov - Colloids and Surfaces A: Physicochemical and …, 2012 - Elsevier
This article describes the influence of the preparation method on the physicochemical
properties of econazole-loaded poly (butyl cyanoacrylate) nanoparticles. The nanoparticles …