Neurological consequences of obesity

PD O'Brien, LM Hinder, BC Callaghan… - The Lancet …, 2017 - thelancet.com
The high prevalence of obesity is associated with an enormous medical, social, and
economic burden. The metabolic dysfunction, dyslipidaemia, and inflammation caused by …

Peripheral neuropathy in prediabetes and the metabolic syndrome

AM Stino, AG Smith - Journal of diabetes investigation, 2017 - Wiley Online Library
Peripheral neuropathy is a major cause of disability worldwide. Diabetes is the most
common cause of neuropathy, accounting for 50% of cases. Over half of people with …

Peripheral neuropathy and all-cause and cardiovascular mortality in US adults: a prospective cohort study

CW Hicks, D Wang, K Matsushita… - Annals of internal …, 2021 - acpjournals.org
Background: Growing evidence indicates that peripheral neuropathy (PN) is common even
in the absence of diabetes. However, the clinical sequelae of PN have not been quantified in …

Diabetic neuropathy: clinical manifestations and current treatments

BC Callaghan, HT Cheng, CL Stables… - The lancet …, 2012 - thelancet.com
Diabetic peripheral neuropathy is a prevalent, disabling disorder. The most common
manifestation is distal symmetrical polyneuropathy (DSP), but many patterns of nerve injury …

Metabolic syndrome and peripheral neuropathy

M Kazamel, AM Stino, AG Smith - Muscle & Nerve, 2021 - Wiley Online Library
Diabetic peripheral neuropathy and metabolic syndrome (MetS) are both global health
challenges with well‐established diagnostic criteria and significant impacts on quality of life …

The epidemiology and risk factors of chronic polyneuropathy

R Hanewinckel, M van Oijen, MA Ikram… - European journal of …, 2016 - Springer
Polyneuropathy is a disabling condition of the peripheral nerves, characterized by
symmetrical distal numbness and paresthesia, often accompanied with pain and weakness …

[HTML][HTML] Risk factors and comorbidities in diabetic neuropathy: an update 2015

N Papanas, D Ziegler - The review of diabetic studies: RDS, 2015 - ncbi.nlm.nih.gov
Distal symmetric sensorimotor polyneuropathy (DSPN) is the most common neurological
manifestation in diabetes. Major risk factors of DSPN include diabetes duration …

Obesity and hyperlipidemia are risk factors for early diabetic neuropathy

AG Smith, JR Singleton - Journal of Diabetes and its Complications, 2013 - Elsevier
Abstract The Utah Diabetic Neuropathy Study (UDNS) examined 218 type 2 diabetic
subjects without neuropathy symptoms, or with symptoms of< 5 years, in order to evaluate …

Neuropathy in prediabetes: does the clock start ticking early?

N Papanas, AI Vinik, D Ziegler - Nature Reviews Endocrinology, 2011 - nature.com
Abstract Between 25% and 62% of patients with idiopathic peripheral neuropathy are
reported to have prediabetes, and among individuals with prediabetes 11–25% are thought …

[PDF][PDF] Small fiber neuropathy: a burning problem

J Tavee, L Zhou - Cleve Clin J Med, 2009 - northwestern.cloud-cme.com
Small fiber neuropathy is increasingly being recognized as a major cause of painful burning
sensations in the feet, especially in the elderly. Although strength remains preserved …