Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor regulating the
expression of genes, for instance encoding the monooxygenases cytochrome P450 (CYP) …

Wildfires are becoming more frequent and destructive in a changing climate. Fine particulate
matter, PM2. 5, in wildfire smoke adversely impacts human health. Recent toxicological …

Environmental exposures interplay with human host factors to promote the development and
progression of allergic diseases. The worldwide prevalence of allergic disease is rising as a …

Nine out of 10 people breathe air that does not meet World Health Organization pollution
limits. Air pollutants include gasses and particulate matter and collectively are responsible …

Airborne particulate matter (PM) comprises both solid and liquid particles, including carbon,
sulphates, nitrate, and toxic heavy metals, which can induce oxidative stress and …

Chronic obstructive pulmonary disease (COPD) is a progressive lung disorder with
substantial patient burden and leading cause of death globally. Cigarette smoke remains to …

Gestational diabetes mellitus (GDM) is a serious complication of pregnancy that could cause
adverse health effects on both mothers and fetuses, and its prevalence has been increasing …

The brake system is one of the most important systems on the vehicle, especially from the
aspect of traffic safety. The use of the braking system comes with many undesirable effects …

Sleep has been associated with aging and relevant health outcomes, but the causal
relationship remains inconclusive. In this study, we investigated the associations of sleep …