Background Knee osteoarthritis (OA) is a chronic progressive disease that imparts a
substantial socioeconomic burden to society and healthcare systems. The prevalence of …

Background: Surgical treatment of symptomatic femoroacetabular impingement (FAI) aims to
improve symptoms and potentially delay initiation of hip osteoarthritis and prevent …

Background Up-regulation of hepatic delta-aminolevulinic acid synthase 1 (ALAS1), with
resultant accumulation of delta-aminolevulinic acid (ALA) and porphobilinogen, is central to …

Background Knowledge of the minimal clinically important difference (MCID) for different
shoulder outcome metrics and range of motion after total shoulder arthroplasty (TSA) can be …

Abstract Purpose The Knee Society Clinical Rating System (KS) is one of the most popular
tools used to assess patient outcome after total knee arthroplasty (TKA), but its minimal …

Abstract Background & Aims Upregulation of hepatic delta‐aminolevulinic acid synthase 1
with accumulation of potentially toxic heme precursors delta‐aminolevulinic acid and …

Importance Opioid use for chronic nonmalignant pain can be harmful. Objective To test
whether a multicomponent, group-based, self-management intervention reduced opioid use …

Background: Highly porous surfaces promoting biologic fixation have renewed interest in
cementless total knee arthroplasty (TKA), but the potential for failed biologic fixation remains …

Background: The minimum clinically important difference (MCID) attempts to define the
patient's experience of treatment outcomes. Efforts at calculating the MCID have yielded …

Background & Aims Acute hepatic porphyria (AHP) is caused by defects in hepatic heme
biosynthesis, leading to disabling acute neurovisceral attacks and chronic symptoms. In …