Structure, gating, and regulation of the CFTR anion channel
The cystic fibrosis transmembrane conductance regulator (CFTR) belongs to the ATP
binding cassette (ABC) transporter superfamily but functions as an anion channel crucial for …
binding cassette (ABC) transporter superfamily but functions as an anion channel crucial for …
Stochastic models for ion channels: introduction and bibliography
FG Ball, JA Rice - Mathematical biosciences, 1992 - Elsevier
Stochastic models for ion channels: Introduction and bibliography - ScienceDirect Skip to main
contentSkip to article Elsevier logo Journals & Books Search RegisterSign in View PDF …
contentSkip to article Elsevier logo Journals & Books Search RegisterSign in View PDF …
[图书][B] Molecular and cellular biophysics
MB Jackson - 2006 - books.google.com
Molecular and Cellular Biophysics provides advanced undergraduate and graduate
students with a foundation in the basic concepts of biophysics. Students who have taken …
students with a foundation in the basic concepts of biophysics. Students who have taken …
Equivalence of aggregated Markov models of ion-channel gating
P Kienker - Proceedings of the Royal Society of London …, 1989 - royalsocietypublishing.org
One cannot always distinguish different Markov models of ion-channel kinetics solely on the
basis of steady-state kinetic data. If two generator (or transition) matrices are related by a …
basis of steady-state kinetic data. If two generator (or transition) matrices are related by a …
Potassium-selective block of barium permeation through single KcsA channels
KN Piasta, DL Theobald, C Miller - Journal of General Physiology, 2011 - rupress.org
Ba2+, a doubly charged analogue of K+, specifically blocks K+ channels by virtue of
electrostatic stabilization in the permeation pathway. Ba2+ block is used here as a tool to …
electrostatic stabilization in the permeation pathway. Ba2+ block is used here as a tool to …
Using independent open-to-closed transitions to simplify aggregated Markov models of ion channel gating kinetics
Deducing plausible reaction schemes from single-channel current traces is time-consuming
and difficult. The goal is to find the simplest scheme that fits the data, but there are many …
and difficult. The goal is to find the simplest scheme that fits the data, but there are many …
Full-fusion and kiss-and-run in chromaffin cells controlled by irreversible vesicle size-dependent fusion pore transitions
Exocytosis operates through two distinct modes. Full-fusion leads to rapid expulsion of the
entire content of a vesicle; kiss-and-run leads to slow and partial expulsion. These two …
entire content of a vesicle; kiss-and-run leads to slow and partial expulsion. These two …
Yet another approach to the dwell-time omission problem of single-channel analysis
SC Crouzy, FJ Sigworth - Biophysical journal, 1990 - cell.com
Distortion of the open-time or closed-time distributions of single channel currents, due to
limited time resolution of the recording system, has been addressed by many authors. The …
limited time resolution of the recording system, has been addressed by many authors. The …
How to resolve microsecond current fluctuations in single ion channels: The power of beta distributions
I Schroeder - Channels, 2015 - Taylor & Francis
A main ingredient for the understanding of structure/function correlates of ion channels is the
quantitative description of single-channel gating and conductance. However, a wealth of …
quantitative description of single-channel gating and conductance. However, a wealth of …
Bayesian inference for ion–channel gating mechanisms directly from single–channel recordings, using Markov chain Monte Carlo
FG Ball, Y Cai, JB Kadane… - Proceedings of the …, 1999 - royalsocietypublishing.org
The gating mechanism of a single–ion channel is usually modelled by a finite–state–space
continuous–time Markov chain. The patch–clamp technique enables the experimenter to …
continuous–time Markov chain. The patch–clamp technique enables the experimenter to …