Review of risk from potential emerging contaminants in UK groundwater

M Stuart, D Lapworth, E Crane, A Hart - Science of the Total Environment, 2012 - Elsevier
This paper provides a review of the types of emerging organic groundwater contaminants
(EGCs) which are beginning to be found in the UK. EGCs are compounds being found in …

The food and environmental safety of Bt crops

MS Koch, JM Ward, SL Levine, JA Baum… - Frontiers in plant …, 2015 - frontiersin.org
Bacillus thuringiensis (Bt) microbial pesticides have a 50-year history of safety in agriculture.
Cry proteins are among the active insecticidal ingredients in these pesticides, and genes …

Understanding the human health effects of chemical mixtures.

DO Carpenter, K Arcaro, DC Spink - Environmental health …, 2002 - ehp.niehs.nih.gov
Most research on the effects of chemicals on biologic systems is conducted on one chemical
at a time. However, in the real world people are exposed to mixtures, not single chemicals …

Dioxin-like and non-dioxin-like toxic effects of polychlorinated biphenyls (PCBs): implications for risk assessment

JP Giesy, K Kannan - Critical reviews in toxicology, 1998 - Taylor & Francis
Polychlorinated biphenyls (PCBs) are persistent, bioaccumulative, and toxic contaminants in
the environment. Individual PCB congeners exhibit different phy sicochemical properties …

Human‐toxicological effect and damage factors of carcinogenic and noncarcinogenic chemicals for life cycle impact assessment

MAJ Huijbregts, LJA Rombouts… - Integrated …, 2005 - Wiley Online Library
Chemical fate, effect, and damage should be accounted for in the analysis of human health
impacts by toxic chemicals in life‐cycle assessment (LCA). The goal of this article is to …

Risk assessment of mixtures of pesticides. Current approaches and future strategies

TK Reffstrup, JC Larsen, O Meyer - Regulatory toxicology and …, 2010 - Elsevier
The risk assessment of pesticide residues in food is based on toxicological evaluation of the
single compounds and no internationally accepted procedure exists for evaluation of …

Toxicological evaluation and risk assessment of chemical mixtures

FR Cassee, JP Groten, PJ Bladeren… - Critical Reviews in …, 1998 - Taylor & Francis
A major objective of combination toxicology is to establish whether a mixture of chemicals
will result in an effect similar to that expected on the basis of additivity. This requires …

Risks to aquatic organisms posed by human pharmaceutical use

MS Kostich, JM Lazorchak - Science of the total environment, 2008 - Elsevier
In order to help prioritize future research efforts within the US, risks associated with exposure
to human prescription pharmaceutical residues in wastewater were estimated from …

Chemical mixtures: considering the evolution of toxicology and chemical assessment

E Monosson - Environmental health perspectives, 2005 - ehp.niehs.nih.gov
The assessment of chemical mixtures is a complex topic for toxicologists, regulators, and the
public. In this article the linkage between the science of toxicology and the needs of …

Assessing the risks of exposures to multiple chemicals with a common mechanism of toxicity: how to cumulate?

CF Wilkinson, GR Christoph, E Julien, JM Kelley… - Regulatory Toxicology …, 2000 - Elsevier
The Food Quality Protection Act (FQPA) of 1996 requires the US EPA to consider the
“cumulative effects” of pesticides and other substances that have a “common mechanism of …