MicroRNAs (miRNAs) are small, non-coding RNAs that post-transcriptionally regulate gene
expression by binding to specific mRNA targets and promoting their degradation and/or …

Extracellular vesicles (EVs) are minute vesicles with lipid bilayer membranes. EVs are
secreted by cells for intercellular communication. Recently, EVs have received much …

Chemokines are a family of cytokines that orchestrate the migration and positioning of
immune cells within tissues and are critical for the function of the immune system. CCR2 …

Fatty liver diseases can result from common metabolic diseases, as well as from xenobiotic
exposure and excessive alcohol use, all of which have been shown to exert toxic effects on …

The generation of vesicles is a constitutive attribute of mitochondria inherited from bacterial
ancestors. The physiological conditions and mild oxidative stress promote oxidation and …

Extracellular vesicles (EVs) are transport vesicles secreted by living cells and released into
the extracellular environment. Recent studies have shown that EVs serve as “messengers” …

Nonalcoholic fatty liver disease (NAFLD), or, more accurately, metabolic associated fatty
liver disease, accounts for a large proportion of chronic liver disorders worldwide and is …

Liver disease is responsible for approximately 1.2 million global deaths per year, which
account for 3.5% of all deaths worldwide.[1] Acute liver injury is often reversible, while …

Bone is the second leading metastatic site for hepatocellular carcinoma (HCC). Patients with
HCC and bone metastasis suffer poor quality of life and reduced survival time. Extracellular …

More than eight hundred million people worldwide have chronic liver disease, with two
million deaths per year. Recurring liver injury results in fibrogenesis, progressing towards …