Increasing evidence shows that liver tumor-initiating cells (T-ICs) closely associated with the
progression, metastasis, recurrence and chemo-resistance of hepatocellular carcinoma …

Muscle Invasive Bladder Cancer (MIBC) is a subset of bladder cancer with a significant risk
for metastases and death. It accounts for nearly 25% of bladder cancer diagnoses. A …

Hepatocellular carcinoma (HCC) is the most common primary malignant liver tumor and a
leading cause of cancer-related deaths worldwide. However, current diagnostic tools are …

Extracellular vesicles (EVs) hold great promise for clinical application as new diagnostic and
therapeutic modalities. This paper describes major GMP-based upstream and downstream …

BACKGROUND Obesity plays a vital role in the occurrence and development of non-
alcoholic steatohepatitis (NASH). However, the underlining mechanism is still unclear …

Extracellular vesicles (EVs) are nanoscopic packages that are heterogeneous and bona fide
players in hepatic physiology and pathology as they are involved in intercellular …

Urine bears high potential for serving as biomarker repository for renal and urinary tract
associated disorders. Besides various metabolites and salts, urine carries extracellular …

Accurate prediction of survival in patients with cirrhosis is crucial, as patients who are
unlikely to survive in the short‐term need to be oriented to liver transplantation and to novel …

Hepatitis B virus (HBV) specifically infects liver cells, leading to progressive liver cirrhosis
and significantly increasing the risk of hepatocellular carcinoma (HCC). The maturity of …

Psychological stress emerges to be a common health burden in the current society for its
highly related risk of mental and physical disease outcomes. However, how the quickly …