[HTML][HTML] Pharmacogenetics of thiopurines
R Franca, G Zudeh, S Pagarin, M Rabusin… - Cancer Drug …, 2019 - ncbi.nlm.nih.gov
Polychemotherapeutic protocols for the treatment of pediatric acute lymphoblastic leukemia
(ALL) always include thiopurines. Specific approaches vary in terms of drugs, dosages and …
(ALL) always include thiopurines. Specific approaches vary in terms of drugs, dosages and …
[HTML][HTML] ITPA, TPMT, and NUDT15 Genetic Polymorphisms Predict 6-Mercaptopurine Toxicity in Middle Eastern Children With Acute Lymphoblastic Leukemia
Background: Acute lymphoblastic leukemia (ALL) is the most common cancer seen in
children worldwide and in the Middle East. Although there have been major advances in …
children worldwide and in the Middle East. Although there have been major advances in …
[HTML][HTML] Protective role of ITPA rs1127354-CA polymorphism against anemia in HCV patients using sofosbuvir ribavirin therapy: age and gender match case-control …
Background: Hepatitis C virus is affecting around 80 million people. Sofosbuvir ribavirin-
based therapy is associated with certain side effects, especially anemia. Inosine …
based therapy is associated with certain side effects, especially anemia. Inosine …
Association of Herpes simplex virus I&II infections with rs187084 SNP of TLR9 and male infertility
M Komijani, HR Momeni, N Shaykh‐Baygloo… - Andrologia, 2021 - Wiley Online Library
Since TLR9 recognises unmethylated CpG motifs in viral DNA, its polymorphisms may
contribute to the susceptibility to Herpes simplex virus I&II infection. In the present study, to …
contribute to the susceptibility to Herpes simplex virus I&II infection. In the present study, to …
[PDF][PDF] Current nutritional factors affecting fertility and infertility
H Cekici - Annals of Clinical and Laboratory Research, 2018 - researchgate.net
Ovulatory fertility is defined as the release of an egg from the ovary, must happen in order to
achieve pregnancy. In case of a defect in the ovulation process, the final result of …
achieve pregnancy. In case of a defect in the ovulation process, the final result of …
[HTML][HTML] Genotyping of rs1127354 and rs7270101 SNPs in Multiple Sclerosis Patients: Correlation with ITPA Gene Expression
Z Shirvani-Farsani, S Fardi, MA Sahraian… - Jentashapir Journal of …, 2024 - brieflands.com
Background: The ITPA gene plays a vital role in maintaining cellular homeostasis by
regulating the levels of inosine triphosphate (ITP) and diphosphate (IDP) within cells …
regulating the levels of inosine triphosphate (ITP) and diphosphate (IDP) within cells …