Effect of prophylaxis for early adrenal insufficiency using low-dose hydrocortisone in very preterm infants: an individual patient data meta-analysis

ML Shaffer, O Baud, T Lacaze-Masmonteil… - The Journal of …, 2019 - Elsevier
Objective To assess the effect of prophylaxis for early adrenal insufficiency using low-dose
hydrocortisone on survival without bronchopulmonary dysplasia (BPD) in very preterm …

Adrenal insufficiency: still a cause of morbidity and death in childhood

DI Shulman, MR Palmert, SF Kemp… - …, 2007 - publications.aap.org
Adrenal insufficiency is relatively rare in childhood and adolescence. Signs and symptoms
may be nonspecific; therefore, the diagnosis may not be suspected early in the course. If …

Prophylaxis of early adrenal insufficiency to prevent bronchopulmonary dysplasia: a multicenter trial

KL Watterberg, JS Gerdes, CH Cole, SW Aucott… - …, 2004 - publications.aap.org
Background. Infants developing bronchopulmonary dysplasia (BPD) show decreased
cortisol response to adrenocorticotropic hormone. A pilot study of low-dose hydrocortisone …

Transient adrenocortical insufficiency of prematurity and systemic hypotension in very low birthweight infants

PC Ng, CH Lee, CWK Lam, KC Ma, TF Fok… - Archives of Disease in …, 2004 - fn.bmj.com
Objectives: A proportion of preterm, very low birthweight (VLBW,< 1500 g) infants may show
inadequate adrenal response to stress in the immediate postnatal period. The human …

Salivary cortisol and mood and pain profiles during skin-to-skin care for an unselected group of mothers and infants in neonatal intensive care

E Mörelius, E Theodorsson, N Nelson - Pediatrics, 2005 - publications.aap.org
Objectives. Mother-infant separation after birth is a well-known source of stress. Parents and
preterm infants in neonatal intensive care are separated immediately after birth. Skin-to-skin …

Postnatal corticosteroids to prevent or treat bronchopulmonary dysplasia

KL Watterberg, Committee on Fetus and Newborn - Pediatrics, 2010 - publications.aap.org
The purpose of this revised statement is to review current information on the use of postnatal
glucocorticoids to prevent or treat bronchopulmonary dysplasia in the preterm infant and to …

A double-blind, randomized, controlled study of a “stress dose” of hydrocortisone for rescue treatment of refractory hypotension in preterm infants

PC Ng, CH Lee, FL Bnur, IHS Chan, AWY Lee… - …, 2006 - publications.aap.org
Objective. To assess the effectiveness of a “stress dose” of hydrocortisone for rescue
treatment of refractory hypotension and adrenocortical insufficiency of prematurity in very …

Relative adrenal insufficiency in the preterm and term infant

EF Fernandez, KL Watterberg - Journal of Perinatology, 2009 - nature.com
Cortisol release in the face of illness or stress is vital for survival. Relative adrenal
insufficiency occurs when a patient's cortisol response is inadequate for the degree of illness …

Placental 11β-hydroxysteroid dehydrogenase-2 and fetal cortisol/cortisone shuttle in small preterm infants

E Kajantie, L Dunkel, U Turpeinen… - The Journal of …, 2003 - academic.oup.com
Glucocorticoids rate among the most controversial topics in today's perinatology and
neonatology. Many sick preterm infants exhibit signs of adrenal insufficiency, the etiology …

Maternal stress and behavior modulate relationships between neonatal stress, attention, and basal cortisol at 8 months in preterm infants

MT Tu, RE Grunau, J Petrie‐Thomas… - Developmental …, 2007 - Wiley Online Library
There is evidence that the developmental trajectory of cortisol secretion in preterm infants is
altered, with elevated basal cortisol levels observed postnatally through at least 18 months …