Influenza antivirals and animal models
CJ Caceres, B Seibert, F Cargnin Faccin… - FEBS open …, 2022 - Wiley Online Library
Influenza A and B viruses are among the most prominent human respiratory pathogens.
About 3–5 million severe cases of influenza are associated with 300 000–650 000 deaths …
About 3–5 million severe cases of influenza are associated with 300 000–650 000 deaths …
Airborne transmission of avian origin H9N2 influenza A viruses in mammals
Influenza A viruses (IAV) are widespread viruses affecting avian and mammalian species
worldwide. IAVs from avian species can be transmitted to mammals including humans and …
worldwide. IAVs from avian species can be transmitted to mammals including humans and …
Block the Spread: Barriers to Transmission of Influenza Viruses
V Le Sage, AC Lowen… - Annual Review of …, 2023 - annualreviews.org
Respiratory viruses, such as influenza viruses, cause significant morbidity and mortality
worldwide through seasonal epidemics and sporadic pandemics. Influenza viruses transmit …
worldwide through seasonal epidemics and sporadic pandemics. Influenza viruses transmit …
Influenza viruses and coronaviruses: Knowns, unknowns, and common research challenges
The development of safe and effective vaccines in a record time after the emergence of the
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a remarkable …
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a remarkable …
Zebrafish-based platform for emerging bio-contaminants and virus inactivation research
Emerging bio-contaminants such as viruses have affected health and environment settings
of every country. Viruses are the minuscule entities resulting in severe contagious diseases …
of every country. Viruses are the minuscule entities resulting in severe contagious diseases …
Development of a monoclonal antibody PMab-292 against ferret podoplanin
N Goto, H Suzuki, T Tanaka, T Asano… - Monoclonal …, 2022 - liebertpub.com
Ferrets (Mustela putorius furo) have been used as small animal models to investigate severe
acute respiratory syndrome coronaviruses (SARS-CoV and SARS-CoV-2) infections …
acute respiratory syndrome coronaviruses (SARS-CoV and SARS-CoV-2) infections …
In Vitro Modelling of Respiratory Virus Infections in Human Airway Epithelial Cells – A Systematic Review
LC Rijsbergen, LLA Van Dijk, MFM Engel… - Frontiers in …, 2021 - frontiersin.org
Respiratory tract infections (RTI) are a major cause of morbidity and mortality in humans. A
large number of RTIs is caused by viruses, often resulting in more severe disease in infants …
large number of RTIs is caused by viruses, often resulting in more severe disease in infants …
Pan-antiviral effects of a PIKfyve inhibitor on respiratory virus infection in human nasal epithelium and mice
J Baker, H Ombredane, L Daly, I Knowles… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Endocytosis, or internalization through endosomes, is a major cell entry mechanism used by
respiratory viruses. Phosphoinositide 5-kinase (PIKfyve) is a critical enzyme for the synthesis …
respiratory viruses. Phosphoinositide 5-kinase (PIKfyve) is a critical enzyme for the synthesis …
Vaccine Strategies to Elicit Mucosal Immunity
Y Song, F Mehl, SL Zeichner - Vaccines, 2024 - mdpi.com
Vaccines are essential tools to prevent infection and control transmission of infectious
diseases that threaten public health. Most infectious agents enter their hosts across mucosal …
diseases that threaten public health. Most infectious agents enter their hosts across mucosal …
Nonrespiratory sites of influenza‐associated disease: mechanisms and experimental systems for continued study
HM Froggatt, NS Heaton - The FEBS journal, 2022 - Wiley Online Library
The productive replication of human influenza viruses is almost exclusively restricted to cells
in the respiratory tract. However, a key aspect of the host response to viral infection is the …
in the respiratory tract. However, a key aspect of the host response to viral infection is the …