Oxidative stress is a major component of cell damage and cell fat, and as such, it occupies a
central position in the pathogenesis of metabolic disease. Nuclear factor-erythroid-derived 2 …

B cell generation of autoantibodies is a crucial step in the pathogenesis of systemic lupus
erythematosus (SLE). After their differentiation in the bone marrow, B cells populate the …

Age-associated B cells (ABCs) are formed under inflammatory conditions and are
considered a type of memory B cell (MBC) expressing the transcription factor T-bet. In SLE …

Autoimmune diseases are characterized by the recognition of self‐antigens by the immune
system, which leads to inflammation and tissue damage. B cells are directly and indirectly …

B cells orchestrate autoimmune responses in patients with systemic lupus erythematosus
(SLE), but broad-based B cell–directed therapies show only modest efficacy while blunting …

Abstract Purpose of the Review Systemic lupus erythematosus (SLE) is driven by nucleic
acid-containing antigens that stimulate endosomal TLRs. We review new advances in our …

Background Systemic lupus erythematosus (SLE) is a complex autoimmune disease
associated with widespread immune dysregulation and diverse clinical features. Immune …

Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune inflammatory disease
that damages multiple organs by the production of autoantibodies. Numerous research …

В настоящее время получены веские доказательства фундаментальной роли
патологической активации В-клеток в патогенезе иммуновоспалительных …

Системная красная волчанка (СКВ)-системное аутоиммунное ревматическое
заболевание неизвестной этиологии, характеризующееся гиперпродукцией …